摘要
为了解萝芙木属植物在中医药领域的研究热点和前沿方向,通过检索中国知网(CNKI)和Web of Science数据库中2002-2022年萝芙木属植物的化学成分、药理活性和临床应用等相关研究文献,利用CiteSpace 6.1.R6软件绘制萝芙木属植物研究的知识图谱,对发文量、作者、研究机构和关键词等进行可视化分析。共筛选纳入中文有效文献173篇,英文有效文献356篇,结果显示年发文量总体上呈波动上升趋势。中、英文文献发文量最多的作者分别为曹福祥和Stockigt J,发文量最多的机构分别为中南林业科技大学和Johannes Gutenberg-Universität Mainz。关键词分析结果显示,萝芙木属植物的研究方向集中于萝芙木属植物的栽培种植和化学成分的提取鉴定及其药理活性的分析,其中中文文献侧重于萝芙木属植物的培育,英文文献侧重于异胡豆苷合酶等化学成分的提取鉴定和各类化学成分药理活性中的抗菌、抗氧化作用。萝芙木属植物的化学成分及其药理活性的深入研究与临床应用实践是未来主要发展趋势。
In order to understand the research hotspots and frontier directions of Rauvolfia in the field of traditional Chinese medicine,the literature about chemical composition,pharmacological activity and clinical application were searched in CNKI and Web of Science databases.CiteSpace 6.1.R6 was used for authors and research institutions co-occurrence,keyword co-occurrence,keyword clustering and keyword timeline mapping and analysis.A total of 173 effective Chinese articles and 356 effective English articles were included,and the annual number of articles showed a fluctuating upward trend overall.The authors with the most publications in Chinese and English were CAO Fuxiang and Stockigt J,respectively.The institutions with the most publications were Central South University of Forestry and Technology and Johannes Gutenberg-Universität Mainz,respectively.The analysis of keywords showed that the research direction of Rauvolfia mainly focused on cultivation,chemical composition extraction,identification and pharmacological activity analysis.Chinese literature focused on the cultivation of various Rauvolfia.English literature focused on the extraction and identification of strictosidine synthase and other chemical components,as well as the antibacterial and antioxidant effects of pharmacological activities of various chemical components.How to rationally use the chemical components of Rauvolfia and study their pharmacological activities and clinical applications are the main trends in the future.
作者
张馨
李林锶
秦新生
ZHANG Xin;LI Linsi;QIN Xinsheng(College of Forestry and Landscape Architecture,South China Agricultural University,Guangzhou 510642)
出处
《北京大学学报（自然科学版）》
EI
CAS
CSCD
北大核心
2023年第6期1011-1024,共14页
Acta Scientiarum Naturalium Universitatis Pekinensis
基金
广东省林业局林业科技创新项目(GDZZDC20228703)资助。
关键词
萝芙木属
文献计量学
药理活性
研究趋势
Rauvolfia
bibliometrics
pharmacological activity
research trends
