摘要
目的通过观察针刺结合自血疗法与西药治疗对慢性荨麻疹临床疗效的差异,为针刺结合自血疗法在慢性荨麻疹的临床治疗中提供依据。方法选取60例符合慢性荨麻疹标准的患者,将病例随机分为治疗组和对照组,每组各30例患者。治疗组予针刺结合自血疗法每周治疗3次,针刺穴位选取百会、印堂,双侧风池、曲池、外关、合谷、血海、足三里、三阴交。针刺结束后行自血疗法,取患者肘正中静脉血4 mL,消毒一侧足三里、血海后,各注入2 mL自体静脉血,每周1次,两侧交替进行,10次为1个疗程。对照组予氯雷他定片10 mg口服,每日1次,共治疗10周。采用荨麻疹患者症状自评量表、焦虑自评量表(SAS)、抑郁自评量表(SDS)、生活质量量表(SF-36)、复发率作为疗效评价指标,评价患者治疗前后及随访1个月的临床症状改变及复发情况。结果治疗后两组荨麻疹患者症状自评量表评分均明显下降,差异具有显著统计学意义(P<0.01);治疗后治疗组症状改善明显优于对照组,差异具有统计学意义(P<0.05);治疗后两组患者焦虑评分、抑郁评分均明显下降,生活质量评分显著上升,差异具有显著统计学意义(P<0.01);治疗后治疗组焦虑、抑郁症状及生活质量改善均优于对照组,但差异不具有统计学意义(P>0.05)。治疗组有效率(100%)优于对照组(78.57%)(P<0.05);治疗组复发率(6.67%)低于对照组(25.00%)(P<0.05)。结论针刺结合自血疗法治疗慢性荨麻疹具有显著疗效,对比西药治疗慢性荨麻疹具有安全、不良反应少、复发率低、有效率高等优势。
Objective To observe the difference in clinical effect of acupuncture combined with selfblood therapy and Western medicine treatment on chronic urticarial,a basis for the clinical treatment of chronic urticaria by acupuncture combined with autologous blood therapy can be provided.Methods A total of 60 patients who met the criteria of chronic urticaria were divided into treatment group and control group,with 30 patients in each group.The treatment group was treated with acupuncture combined with selfblood therapy for 3 times a week.Acupuncture points include Baihui(GU20),Yintang(GU29),bilateral Fengchi(GB20),Quchi(LI11),Waiguan(SJ5),Hegu(LI4),Xuehai(SP10),Zusanli(ST36)and Sanyinjiao(SP6).After the end of acupuncture,self-blood therapy was performed,4 mL of the patients'cubital median venous blood was extracted,and after disinfection of Zusanli(ST36)and Xuehai(SP10)on one side,2 mL of autologous venous blood was injected into each,once a week,alternately on both sides,10 times as a course of treatment.The control group was received loratadine tablet 10 mg orally,once a day,for 10 weeks.Urticaria self-rating symptom scale,self-rating anxiety scale(SAS),self-rating depression scale(SDS),quality of life scale(SF-36)and recurrence rate were used as curative effect evaluation indicators.The clinical symptoms and recurrence were followed up for 1 month.Results After treatment,the scores of self-rating symptom scale of urticaria patients in the two groups were significantly decreased,and the difference was statistically significant(P<0.01);After treatment,the improvement of symptoms in the treatment group was significantly better than that in the control group,with statistical significance(P<0.05);After treatment,the anxiety scores and depression scores of the two groups were significantly decreased,and the quality of life scores were significantly increased,and the difference was statistically significan(t P<0.01);After treatment,the improvement of anxiety and depression symptoms and quality of life in the acupuncture combined with the treatment group were better than those in the control group,but the difference was not statistically significant(P>0.05).The effective rate of treatment group(100%)was better than that of control group(78.57%),with statistical significance(P<0.05).Follow-up after treatment,the recurrence rate of treatment group(6.67%)was lower than that of control group(25.00%),with statistical significance(P<0.05).Conclusion Acupuncture combined with self-blood therapy is effective in treating chronic urticaria.Compared with Western medicine,chronic urticaria has the advantages of safety,less adverse reactions,low recurrence rate and high efficiency.
作者
彭拥军
王天赐
郭琴
曾春利
胡津丽
PENG Yongjun;WANG Tianchi;GUO Qin;ZENG Chunli;HU Jinli(Affiliated Hospital of Nanjing University of Traditional Chinese Medicine,Nanjing 210029,Jiangsu,China)
出处
《辽宁中医药大学学报》
CAS
2023年第4期5-8,共4页
Journal of Liaoning University of Traditional Chinese Medicine
基金
江苏省中医院高峰学术人才项目(k2021rc24)
江苏省第六期“333高层次人才培养工程”项目
第六批全国老中医药专家学术经验继承人项目(国中医药人教发〔2017〕29号)。
关键词
慢性荨麻疹
针刺
自血疗法
氯雷他定
chronic urticaria
acupuncture
self-blood therapy
loratadine
