摘要
磁性纳米Fe3O4颗粒(MNP-Fe3O4)作为药物载体在肿瘤治疗领域受到广泛关注。综述了目前MNP-Fe3O4的研究现状,重点阐述了该材料的表面改性目的与改性途径,介绍了MNP-Fe3O4不同载药系统在肿瘤治疗中的应用,并详细阐述了介孔结构的MNP-Fe3O4颗粒作为药物载体的优势,指出了MNP-Fe3O4在肿瘤治疗中仍需解决的问题和发展趋势。
Magnetic Fe304 nanoparticles （MNP Fe304 ） have many attracted many attentions in cancer therapy. The present paper reviews the research status of MNP Fe304, mainly focusing on the purpose and methods of Fe304surface modification and the application of different MNP-Fe304 drug delivery systems in cancer therapy. The great potential application of mesoporous MNP-Fe304 is also reviewed and discussed. Finally, the potential problems and trends of MNP-Fe3 04 as drug carrier in cancer therapy are proposed.
出处
《材料导报》
EI
CAS
CSCD
北大核心
2013年第1期44-49,共6页
Materials Reports
基金
重庆市自然科学基金(2010BB5050)
中央高校基本科研业务费
关键词
磁性纳米Fe3O4颗粒
表面改性
药物载体
靶向输送
肿瘤
magnetic Fe304 nanoparticles, surface modification, drug carrier, targeted delivery, cancer
