摘要
目的探讨妊娠期高血压疾病(妊高症)患者临床血脂代谢变化特点。方法选择2009年1月-2010年12月妊高症患者64例、正常妊娠孕妇64例及正常未妊娠妇女20例为研究对象,比较3组对象血液中血脂代谢相关指标,三酰甘油(triglycefide,TG)、总胆固醇(,total cholesterol,TC)、高密度脂蛋白(high density lipoprotein,HDL)、低密度脂蛋白(10w density lipoprotein,LDL)、载脂蛋白A1(apolipoprotein A1,ApoAl)、载脂蛋白B(apolipoprotein B,ApoB)和脂蛋白α(apolipoprotein α,LPα)的含量差异。结果 2个妊娠组与正常未孕组相比,TG、TC、LDL、ApoAl、ApoB和LPα等均显著升高(P<0.05),HDL差异无统计学意义(P>0.05);妊高症组与正常妊娠组相比,TG、TC、LDL、ApoAl、ApoB和LPα等均显著增高(P<0.05),而HDL降低(P<0.05)。结论妊高症患者与正常妊娠妇女和正常未妊娠妇女的血脂代谢存在明显差异,其为检测、诊断和预防该病提供了理论依据。
Objective To investigate the characters of blood lipid metabolism in patients with hypertensive disorder complicating pregnancy. Methods Sixty - four patients with hypertensive disorder complicating pregnancy, 64 normal pregnancy women and 20 normal nulli -pregnancy women were selected as research object. The blood lipid metabolism indexes such as ： triglyceride （ TG ）, total cholesterol（ TC ）, high density lipoprotein （ HDL ）, low density lipoprotein （ LDL ）, apolipoprotein A1 （ApoA1）, apolipoprotein B（ApoB） and apolipoprotein or（Lpcx） were compared. Results The TG,TC, LDL,ApoA1, ApoB and Lpc~ of the two pregnacy groups were higher than those of normal nulli - pregnancy woman （ P 〈 0.05 ）. The TG, TC, LDL, ApoA1, ApoB and Lpα of patients with hypertensive disorder complicating pregnancy were higher than those of normal pregnancy woman （ P 〈 0.05 ）. But HDL was significantly decreased. Conclusion The blood lipid metabolism of patients with hypertensive disorder complicating pregnancy has significant difference from that of normal pregnancy women and nulli -pregnancy women. And it can provide theoretical basis for detection, diagnosis, and prevention of hypertensive disorder complicating pregnancy.
出处
《河北医科大学学报》
CAS
2011年第10期1143-1144,共2页
Journal of Hebei Medical University
关键词
高血压
妊娠性
血脂异常
诊断
hypertension, pregnancy - induced
dyslipidemia
diagnosis
