摘要
目的了解脂蛋白-胆固醇代谢和妊娠高血压综合征（妊高征）的关系。方法对正常孕妇及妊高征孕妇，分别于妊娠中期、晚期及脐血测定载脂蛋白A(apolipoproteinAPO－A）、载脂蛋白B（apolipoproteinB,APO－B）、高密度脂蛋白-胆固醇（highdensitylipoprotein－choesterol，HDL－C）、低密度脂蛋白-胆固醇（lowdensitylipoprotein－cholesterol，LDL－C）的值。结果APO－A和HDL－C的值妊高征组和正常妊娠组比较，无显著差异。LDL－C和APO－B的值随着妊娠孕周的增加而增高。妊高征组和正常妊娠组相比较，ARJ－B在孕中期、晚期和脐血中的水平妊高征组均高于对照组，均有显著差异；妊高征组LDL－C于孕晚期高于正常妊娠组，P＜0．05。结论低密度脂蛋白-胆固醇代谢异常及高水平和妊高征发病有关。
Obective To discuss the relationship between metabolism of lipoprotein - cholesterol and Pregnancy induced hypertension(PIH). Methods The contents of apolipoprotein A(APO - A), apolipoprotein B(APO - B), high density lipoprotein - cholesterol (HDL - C) and low density lipoprotein - choesterol(LDL - C) in matemal and umbilical vein of pregnant induced hypertension and the norml pregnant women in the second and third trimester were measured.Results The levels of APO - A and HDL- Cwere not significantly changed betwee the group of pregnancy induced hypertension and normal pregnancy. The levels of LDL - C and APO - B were increasing with gestational age developing.APO - B in the second, third trimester and umbilical blood were obviously higher than that of the control group. LDL - C of PIH group in the third trimester was obviously higher, P ＜0 .05. belusion Our results showed metaboic disorder and high level of low density lipoprotein - cholesterol was associated with pregnncy induced hypertension.
出处
《中国实用妇科与产科杂志》
CAS
CSCD
北大核心
1999年第11期731-733,共3页
Chinese Journal of Practical Gynecology and Obstetrics
关键词
妊娠高血压
综合征
载脂蛋白
脂蛋白
胆固醇
Pregnancy induced hypertension Apolipoprotein A Apolipoprotein B High density lipoproteincholesterol Low density lipoprotein - cholesterol
