摘要
目的:探讨中西医结合治疗颌面部慢性化脓性炎症的临床效果。方法:颌面部慢性化脓性炎症患者共52例,按照随机数字的方法分为两组,对照组和观察组,每组26例,对照组使用西医治疗方法,观察组在对照组治疗方法基础上使用中药联合治疗,对治疗的效果进行分析。结果:对照组中痊愈10例,显效11例,无效5例,观察组中痊愈14例,显效12例,无效0例,观察组的治疗效果优于对照组患者,数据差异具有统计学意义(z=-6.343,P<0.05),对照组痊愈的时间为(10.27±1.83)d,显效的时间为(9.84±1.41)d,观察组痊愈的时间为(8.04±0.98)d,显效的时间为(8.01±0.87)d,观察组的痊愈时间和显效时间均短于对照组,数据差异均具有统计学意义(t=3.869,3.783,P<0.05),经过治疗后,对照组的血清C反应蛋白从(15.22±2.81)mg/L降低为(5.61±0.81)mg/L,白细胞介素-4从(4.42±0.64)ng/L升高为(13.27±3.51)ng/L,白细胞介素-6从(66.71±8.36)ng/L降低为(19.68±3.57)ng/L,肿瘤坏死因子-α从(88.56±6.27)ng/L降低为(50.26±7.28)ng/L,观察组的血清C反应蛋白从(15.31±3.08)mg/L降低为(2.35±0.71)mg/L,白细胞介素-4从(4.56±0.71)ng/L升高为(19.57±4.44)ng/L,白细胞介素-6从(67.51±7.61)ng/L降低为(11.85±2.81)ng/L,肿瘤坏死因子-α从(89.71±5.94)ng/L降低为(23.47±4.64)ng/L,观察组各类血清炎性因子改善的幅度均优于对照组,数据差异均具有统计学意义(t=15.433,-5.676,8.788,15.823,P<0.05)。结论:使用中西医结合的方法治疗颌面部慢性化脓性炎症患者,可以提升治疗效果,缩短恢复时间。
Objective:To explore the clinical effect of integrated traditional Chinese and Western medicine in treating chronic suppurative inflammation in maxillofacial region.Methods:52 patients with chronic suppurative inflammation of the maxillofacial region with.According to the random number method,52 patients with were divided into the control group and the observation group,with 26 patients in each group.The patients in the control group were treated with Western medicine,and those in the observation group were treated with traditional Chinese medicine on the basis of the treatment methods of the control group,and the effect of the treatment was analyzed.Result:In the control group,10 patients were cured,11 markedly effective,5 invalid and 14 patients in the observation group were cured,12 markedly effective and 0 invalid.The treatment effect of the observation group was better than that of the control group,and the difference was statistically significant(z=-6.343,P<0.05).The cure time of the control group was(10.27±1.83)d,and the effective time was(9.84±1.41)d.The recovery time of the observation group was(8.04±0.98)d,and the effective time was(8.01±0.87)d.The recovery time and effective time of the observation group were shorter than those of the control group,and the difference was statistically significant(t=3.869,3.783,P<0.05).After treatment,the serum C reactive protein of the control group decreased from(15.22±2.81)mg/L to(5.61±0.81)mg/L,and interleukin-4 increased from(4.42±0.64)ng/L to(13.27±3.51)ng/L,and interleukin-6 decreased from(66.71±8.36)ng/L to(19.68±3.57)ng/L,tumor necrosis factor-αdecreased from(8.56±6.27)ng/L to(50.26±7.28)ng/L.The serum C reactive protein of the patients in the observation group decreased from(15.31±3.08)mg/L to(2.35±0.71)mg/L,interleukin-4 increased from(4.56±0.71)ng/L to(19.57±4.44)ng/L,and interleukin-6 decreased from(67.51±7.61)ng/L to(11.85±2.81)ng/L,and TNF-αdecreased from(89.71±5.94)ng/L to(23.47±4.64)ng/L.The improvement of all kinds of serum inflammatory factors in the observation group was better than those of the control group,and the difference of the data was statistically significant(t=15.433,-5.676,8.788,15.823,P<0.05).Conclusion:The treatment of chronic suppurative inflammation in the maxillofacial region by combination of traditional Chinese and Western medicine can improve the therapeutic effect and shorten the recovery time.
作者
周涛
钱永
刘韦淞
邓达
赵方腾
ZHOU Tao;QIAN Yong;LIU Weisong;DENG Da;ZHAO Fangteng(Department of Head and Neck Surgery,Hainan Cancer Hospital,Haikou 570312,Hainan,China)
出处
《中华中医药学刊》
CAS
北大核心
2019年第6期1429-1432,共4页
Chinese Archives of Traditional Chinese Medicine
基金
海南省自然科学基金项目(817369)
关键词
颌面部
化脓性炎症
感染
抗生素
maxillofacial
pyogenic inflammation
infection
antibiotics
