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盐酸莫西沙星氯化钠注射液联合常规疗法治疗慢性阻塞性肺疾病的疗效及炎症反应的效果

Efficacy of Moxifloxacin Hydrochloride and Sodium Chloride Injection Combined with Conventional Therapy in the Treatment of Chronic Obstructive Pulmonary Disease and the Effect of Inflammation
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摘要 目的分析盐酸莫西沙星氯化钠注射液联合常规疗法治疗慢性阻塞性肺疾病(COPD)的疗效及炎症反应的效果分析。方法选择2023年1月至2024年3月福建省闽清县总医院接诊的110例COPD患者为研究对象,按照随机数字表法对患者实施分组,对照组(55例)患者在接受治疗的过程中采用常规对症治疗的方式,观察组(55例)患者在接受治疗的过程中需要采用盐酸莫西沙星氯化钠注射液联合常规疗法。对比两组患者的临床症状改善时间、治疗后的血清炎症因子水平、并发症发生率。结果观察组患者接受治疗后,临床症状的改善时间早于对照组患者(P<0.05)。观察组患者接受治疗后,炎症因子水平整体低于对照组患者(P<0.05)。观察组患者接受治疗后,不良反应的发生率低于对照组患者(P<0.05)。结论在实际治疗COPD患者的过程中,应用盐酸莫西沙星氯化钠注射液联合常规疗法,不仅能缩短患者的临床症状改善时间,降低患者的炎症因子水平,还能降低患者的不良反应发生率。 Objective To analyze the efficacy of moxifloxacin hydrochloride and sodium chloride injection combined with conventional therapy in the treatment of chronic obstructive pulmonary disease(COPD)and the effect of inflammation.Methods A total of 110 COPD patients received from January 2023 to March 2024 were selected as the study objects.Patients in the control group(55 cases)were treated with conventional symptomatic treatment,while patients in the observation group(55 cases)were treated with moxifloxacin hydrochloride and sodium chloride injection combined with conventional therapy.To compare the time to improvement of clinical symptoms,serum inflammatory factor levels after treatment,and complication rates between the two groups.Results After treatment,the improvement time of clinical symptoms in observation group was earlier than that in control group(P<0.05).After treatment,the level of inflammatory factors in observation group was lower than that in control group(P<0.05).After treatment,the incidence of adverse reactions in observation group was lower than that in control group(P<0.05).Conclusions In the actual treatment of COPD patients,the application of moxifloxacin hydrochloride and sodium chloride injection combined with conventional therapy can not only shorten the improvement time of clinical symptoms,reduce the level of inflammatory factors in patients,but also reduce the incidence of adverse reactions in patient.
作者 黄奋 HUANG Fen(Department of Pharmacy,Minqing General Hospital,Fuzhou 350800,China)
出处 《中国医药指南》 2024年第36期92-94,共3页 Guide of China Medicine
关键词 盐酸莫西沙星氯化钠注射液 常规疗法 慢性阻塞性肺疾病 疗效 Moxifloxacin hydrochloride and sodium chloride injection Conventional therapy Chronic obstructive pulmonary disease Curative effect
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