摘要
目的:肝癌对于居民的身心健康造成了严重危害。本研究通过对2016—2021年河北省城市居民的高危和筛查数据进行分析,从而为肝癌筛查和早诊早治提供数据支持。方法:按照河北省城市癌症早诊早治中肝癌筛查流程,在石家庄市、唐山市和邢台市选定社区年龄40~74岁的当地居民,通过问卷调查之后采用国家统一评估模型评估出高危人群,进一步通过甲胎蛋白和腹部超声检查,发现早期肝脏病变,必要时通过病理进行确诊。结果:2016—2021年河北省共有190031进行了高危评估,肝癌高危人数为27217人,高危率为14.32%,其中15054人参与了城癌项目肝癌筛查,筛查参与率达到了55.31%,共筛查出肝硬化46例,肝占位性病变106例,肝癌及疑似肝癌4例,检出率分别为0.31%、0.71%、0.027%。女性、55~59岁、体质量指数(BMI)异常、目前吸烟、目前饮酒的人群筛查参与率更高。乙肝表面抗原阳性者的肝硬化检出率是阴性者的17.32倍,甲胎蛋白阳性者的肝硬化检出率是阴性者的7.73倍。结论:应加强肝癌防治知识的健康教育,提高肝癌高危人群,尤其是乙肝表面抗原阳性人群的肝癌筛查参与率,提高肝癌及肝脏良性疾病检出率,从而降低肝癌发病率和死亡率,提高生存率。
Objective:Liver cancer causes serious harm to the physical and mental health of residents.In this study,the high-risk and screening data of urban residents in Hebei Province from 2016 to 2021 were analyzed to provide data support for liver cancer screening and early diagnosis and treatment.Methods:According to the liver cancer screening process for early diagnosis and early treatment of urban cancer in Hebei Province,local residents aged 40 to 74 years in selected communities in Shijiazhuang,Tangshan and Xingtai were assessed by a national unified assessment model after questionnaires.Further through alphafetoprotein and abdominal ultrasonography,early liver lesions were found,and the diagnosis was confirmed by pathology if necessary.Results:In 2016—2021,a total of 190031 people in Hebei Province underwent high-risk assessment.The number of people at high risk of liver cancer was 27217,and the high-risk rate was 14.32%.Among them,15054 people participated in the liver cancer screening of the urban cancer project,and the screening participation rate reached 55.31%.A total of 46 cases of liver cirrhosis,106 cases of liver space-occupying lesions,and 4 cases of liver cancer and suspected liver cancer were screened out,the detection rates were 0.31%,0.71%,and 0.027%,respectively.Females,55-59 years old,abnormal BMI,current smokers,and current drinkers have higher screening participation rates.The detection rate of liver cirrhosis in HBsAg positive patients was 17.32 times that of negative patients,and the detection rate of liver cirrhosis in AFP positive patients was 7.73 times that of negative patients.Conclusions:Health education on the knowledge of liver cancer prevention and treatment should be strengthened,and the participation rate of liver cancer screening among high-risk groups,especially HBsAg-positive people,should be increased,and the detection rate of liver cancer and benign liver diseases should be increased,thereby reducing the incidence and mortality of liver cancer and improving the survival rate.
作者
杜新宇
梁迪
师金
吴思奇
贺宇彤
DU Xinyu;LIANG Di;SHI Jin;WU Siqi;HE Yutong(Hebei Medical University Fourth Affiliated Hospital and Hebei Provincial Tumor Hospital,Shijiazhuang 050000,Hebei,China.)
出处
《健康体检与管理》
2022年第3期209-216,共8页
Journal of Health Examination and Management
基金
河北省自然科学基金项目(J200017)。
关键词
肝癌
筛查
肝硬化
乙肝表面抗原
甲胎蛋白
Liver cancer
Screening
Liver cirrhosis
Hepatitis B surface antigen
Alpha-fetoprotein
