摘要
原发性肝癌患者诊断时多已为中晚期,失去最佳治疗时机,而提高原发性肝癌的早期诊断率对于改善患者预后具有重要意义。新型血清肿瘤标志物的研究进展迅速,但临床应用仍有不太理想之处,根据原发性肝癌高危人群病史信息和常规筛查指标等多因素综合早期风险预测进行风险再分层,针对不同风险等级采取相应的筛查方式,有利于增加患者依从性,进而提高原发性肝癌的早期诊断率。就目前原发性肝癌早期诊断现状及高危人群早期筛查方法和早期发病风险预测等方面的研究进展进行阐述。
Most patients with primary liver cancer are in the advanced stage at diagnosis and have missed the best timing of treatment,and therefore,increasing the early diagnostic rate of primary liver cancer has great significance in improving patients＇ prognosis. There is a rapid progress in the research on new serum tumor markers,but their clinical application is still not satisfactory. The screening method of risk re-stratification based on the medical history of individuals at a high risk of primary liver cancer and conventional screening indices and adoption of different ways of screening based on the level of risk can improve patient compliance and thus increase the early diagnostic rate of primary liver cancer. This article reviews the research advances in the current status of early diagnosis of primary liver cancer,the early screening methods in the high-risk population,and early risk prediction.
作者
罗心晨
周友乾
LUO Xinchen;ZHOU Youqian(Department of Infectious Diseases,169 Hospital of PLA ＆ Xiangnan Hospital Affiliated to Hunan Normal University,Hengyang,Hunan 421002,China)
出处
《临床肝胆病杂志》
CAS
北大核心
2018年第8期1788-1792,共5页
Journal of Clinical Hepatology
关键词
肝肿瘤
病人依从
早期诊断
综述
liver neoplasms
patient compliance
early diagnosis
review
