摘要
蚊虫是登革热、疟疾等疾病病原的重要传播媒介,因其防控的艰巨性给全球人类健康造成巨大威胁。传统蚊虫防控主要采用化学防控策略,化学药剂造成的环境污染以及蚊虫对化学药剂抗性的产生,亟需探索新的蚊虫防控策略。微生物和基因编辑是很有前景的2种蚊虫防控新策略,两者都可以通过抑制或者修饰蚊虫种群来达到蚊媒病原防控的目的。本文将详细阐述上述2种蚊媒病原防控策略,并基于现有的研究进展阐述其作用机理。
Mosquito-borne diseases,such as dengue and malaria,pose significant global health burdens.Chemical control is the most traditional mosquito control strategy.Chemical insecticides cause serious environmental pollution,and mosquitos are evolving drug resistance.Thus,it is urgent to explore new mosquito control strategies.Symbiont and genetic engineering are two promising new strategies.Symbionts and genetic engineering can control mosquito populations either by population suppression or population modification.This review focused on the above two strategies and discussed the latest research progresses.
作者
李维华
姜鹤
王关红
Li Weihua;Jiang He;Wang Guanhong(State Key Laboratory of Integrated Management of Pest Insects and Rodents,Institute of Zoology,Chinese Academy of Sciences,Beijing 100101,China)
出处
《植物保护学报》
CAS
CSCD
北大核心
2022年第1期231-239,共9页
Journal of Plant Protection
基金
中国科学院B类先导科技专项(XDPB16)
农业虫害鼠害综合治理研究国家重点实验室开放课题(IPM2117)。
关键词
蚊媒病原
基因编辑
微生物
基因驱动
蚊虫防控
mosquito-borne diseases
gene editing
symbiotic microorganisms
gene drive
mosquito prevention and control
