摘要
目的:评价静脉注射人免疫球蛋白(IVIG)在儿科患者超适应证用药情况,为临床合理使用IVIG提供参考。方法:回顾性分析某三级甲等妇幼保健院2018年11月至2019年4月135例住院患儿使用IVIG的情况,依据药品说明书和相关临床治疗指南,评价其超适应证用药情况。结果:135例使用IVIG的住院患儿中,以28 d~3岁患儿居多,其中超适应证用药占75.56%,主要用于感染性疾病的治疗和预防,超适应证用药中有循证医学证据支持的为16.67%。结论:儿科超适应证使用IVIG的情况普遍存在,应加强IVIG使用的监管力度,促进IVIG的合理使用。
Objective:To evaluate the off-indication drug use of intravenous immunoglobulin(IVIG)in pediatrics,so as to provide reference for the rational use of IVIG in clinic.Methods:Retrospective analysis was performed on 135 hospitalized children with IVIG in a gradeⅢlevel A maternal and child health care hospital from Nov.2018 to Apr.2019.According to the drug instructions and related clinical treatment guidelines,off-indication drug use was evaluated.Results:Among the 135 hospitalized children with IVIG,most children were aged from 28 d to 3 years.And 75.56%was off-indication drug use,mainly used for the treatment and prevention of infectious diseases.Of the off-indication drug use,16.67%was supported by evidence-based medicine.Conclusion:The off-indication drug use of IVIG in pediatric is common,and the supervision of IVIG should be strengthened to promote the rational use of IVIG.
作者
刘姗娟
Liu Shanjuan(Jingzhou Maternal and Child Health Care Hospital,Hubei Jingzhou 434020,China)
出处
《儿科药学杂志》
CAS
2021年第5期40-42,共3页
Journal of Pediatric Pharmacy
