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大剂量静脉滴注丙种球蛋白治疗新生儿ABO溶血病的疗效观察 被引量:6

Investigation on ABO hemolytic disease of the newborn treated with numerous intravenous droping gammaglobulin.
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摘要 目的 观察大剂量静脉滴注丙种球蛋白(IVIG)治疗新生儿ABO溶血病的临床效果。方法 对符合新生儿ABO溶血病诊断标准且无其它合并症的63例患儿,分为常规治疗组和大剂量IVIG治疗组。IVIG治疗组在常规治疗的基础上给予IVIG80 0mg/kg·d静脉滴注,每日一次,连续3日。结果 IVIG治疗组在治疗前血清胆红素水平比较高的情况下,黄疸消退时间为4 1 8±1 0 3天,常规治疗组为5 .2 8±1 .5 0天,t=3.72 4 ,P <0.0 1。 Objective Investigation on ABO hemolytic disease of the newborn treated with numerous intravenous droping gammaglobulin. Methods 63 cases with ABO hemolytic disease of the newborn without complication. They were divided into two groups: the treatment group and the treatment of gammaglobulin group. The dosage of gammaglobulin 800 mg/kg·d qd×3 days. Results The bilirubinemia regressive time was 4.18±1.03 days in the treatment of gammaglobulin group. The other group was 5.28±1.50 days. t=3.724, P<0.01. Conclusion The numerous intravenous droping gammaglobulin was effective in ABO hemolytic disease of newborn.
作者 汪俭 郑洪
出处 《中国小儿血液》 2005年第2期62-63,共2页 China Child Blood
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