摘要
目的:调查西藏自治区八宿县农村成年人慢性肾脏病(CKD)的流行病学特点,为该地区和西藏高原地区CKD防治提供依据。方法:采取整群分层随机抽样的调查方法,于2019年6~12月选取八宿县2个乡16个行政村年龄大于20周岁的人群进行CKD及相关因素的问卷调查、体格检查及血尿指标检测,并进行统计分析。结果:2271例资料完整的调查对象中,CKD共426例,患病率18.76%,并随年龄增加而升高,女性高于男性,其中蛋白尿、血尿、肾功能下降(eG FR下降)患病率依次为13.83%、9.60%、8.72%,CKD的知晓率和治疗率分别为12.44%和6.81%。多因素Logistic回归分析显示CKD与女性、高龄、吸烟、饮酒、高血压、糖尿病、肥胖、高脂血症和高尿酸血症等因素独立相关。结论:西藏自治区八宿县农村成年人群存在CKD患病率高,知晓率和治疗率低的特点,需重视藏区居民CKD的早期预防宣教和积极干预,重视与CKD相关慢性病的治疗,降低终末期肾脏病的发生。
Objective:To investigate the prevalence and risk factors of chronic kidney disease(CKD)among the adult population in Baisu county,Tibet autonomous region.These results are expected to provide a basis for the prevention and treatment of CKD in this area and the whole Tibetan plateau.Methods:By using stratified cluster random sampling method,we enrolled permanent residents who were older than 20 years among 16 administrative villages from 2 townships from June to December in 2019.Questionnaires of risk factors of CKD and somatoscopy were carried out.Their blood and urine indicators were measured.Results:Eligible data of 2271 subjects were enrolled in this study.426 subjects were diagnosed CKD with a prevalence rate of 18.76%.This prevalence increased with age and higher prevalence was seen in females than in males(P<0.05).Among which,the prevalence of proteinuria,hematuria,reduced eG FR,were 13.83%,9.60%,8.72%,respectively.Results from the logistic regression analysis showed that the independent risk factors of CKD were female,age,smoking,drinking,hypertension,diabetes,obesity,hyperlipidemia and hyperuricemia.Conclusion:The rural adult population in baisu county has the characteristics of high prevalence of CKD,low awareness rate and low treatment rate.Attention should be paid to the early prevention education and the active intervention of CKD in Tibetan residents.Attention should also be paid to the treatment of chronic diseases related to CKD.Based on the above,we can reduce the occurrence of the end-stage renal disease.
作者
刘楠梅
李红仙
赵枢
索朗拉姆
白玛贡桑
洛松曲措
向西
LIU Nanmei;LI Hongxian;ZHAO Shu(Internal MedicineⅢ(Nephrology&Endocrinology),Naval Medical Center of PLA,Shanghai,200052)
出处
《中国中西医结合肾病杂志》
2021年第1期14-18,共5页
Chinese Journal of Integrated Traditional and Western Nephrology
基金
全军医学科技青年培育拔尖项目基金(No.19QNP017)
上海市长宁区重点专科建设项目基金资助(No.20191005)。
关键词
慢性肾脏病
患病率
流行病学
西藏自治区
影响因素
Chronic kidney disease
Prevalence
Epidemiology
Tibet autonomous region
Influence factors