摘要
目的分析早期应用大剂量尿激酶溶栓治疗脑梗死患者的实际临床效果。方法选择本院收治的发病6小时内符合尿激酶溶栓的44例脑梗死患者作为此次研究的对象,为44例患者开展早期静滴NS100 ml+尿激酶150万U单位大剂量尿激酶溶栓治疗,对44例患者治疗前后神经功能缺损评分、BI指数、不良反应和治疗总有效率进行对比和分析。结果治疗后,44例患者神经功能缺损评分显著低于治疗前,P <0.05;治疗后患者BI指数显著提高,P <0.05;44例患者中共计3例患者发生不良反应,不良反应发生率为6.82%;治疗后患者总有效率为90.91%。结论早期大剂量尿激酶溶栓治疗脑梗死效果显著。
Objective To analyze the clinical effect of early treatment of cerebral infarction with high-dose urokinase thrombolysis.Methods Fortyfour patients with cerebral infarction who met urokinase thrombolysis within 6 hours after admission were enrolled in this study.For 44 patients,early intravenous infusion of NS 100 ml+urokinase 1.5 million U units of high-dose urokinase was performed.Suppository therapy was used to compare and analyze the neurological deficit score,BI index,adverse reactions and total effective rate of treatment before and after treatment in 44 patients.Results After treatment,the neurological deficit scores of 44 patients were significantly lower than those before treatment,P<0.05.After treatment,the BI index were significantly increased,P<0.05;A total of 3 patients occurred adverse reactions in 44 patients,the incidence of adverse reactions was 6.82%;The total effective rate after treatment was 90.91%.Conclusion Early high-dose urokinase thrombolysis has significant effects on cerebral infarction.
作者
陈荣平
奉继运
马小梅
CHEN Rongping;FENG Jiyun;MA Xiaomei(Department of Neurology,Lianzhou People's Hospital,Lianzhou Guangdong 513400,China)
出处
《中国卫生标准管理》
2019年第1期78-80,共3页
China Health Standard Management
关键词
脑梗死
大剂量尿激酶
溶栓治疗
神经功能缺损评分
BI指数
不良反应
cerebral infarction
high-dose urokinase
thrombolytic therapy
neurological deficit score
BI index
adverse reactions
