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大剂量尿激酶溶栓治疗急性脑梗死临床研究 被引量:4

Clinical study of effect of urokinese on acute cerebral infarction
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摘要 目的研究尿激酶早期溶栓治疗急性脑梗死的临床疗效。方法93例发病12h以内的脑梗死患者,随机分为尿激酶溶栓治疗组56例,对照组37例,疗程14d,治疗前后以临床表现和CT扫描进行对比分析,观察其疗效。结果溶栓治疗组治愈率50.00%,总有效率91.07%;症状出现后3h内进行溶栓治疗,效果最好,治愈率73.68%,总有效率100%;对照组治愈率10.81%,总有效率75.67%。结论早期尿激酶溶栓治疗急性脑梗死安全、有效。 [Objective] To explore the efficacy of urokinase in the early thrombolysis treatment of acute cerebral infarction. [Method] Ninety-three patients within 12 hours after onset of cerebral infarction were randomly divided into urokinase therapy group (56 cases) and control group (37 cases). They were treated for 14 days, Before and after treatment, the clinical situation and CT image were analysed and the effect was evaluated. [Results] In urokinaes therapy group, the curative rate was 50% and the total effective rate was 91.07%. Particularly, the best efficacy of urokinase thrombolysis was observed in patients treated in 3 hours after diagnosis of cerebral infarction, and the curative rate was 73.68% and the total effective rate was 100%. In control group, the curative rate was 10.8% and the total effective rate was 75.67%. [Conclusion] Urokinase in the early thrombolysis treatment of acute cerebral infarction is safe and effective.
出处 《中国现代医学杂志》 CAS CSCD 北大核心 2006年第8期1263-1264,1271,共3页 China Journal of Modern Medicine
关键词 脑梗死 早期溶栓 尿激酶 cerebral infarction thrombolysis urokinase
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