摘要
目的:比较丙泊酚与七氟烷对小儿腹股沟疝腹腔镜手术的效果及安全性。方法:选择2014年1月至2016年12月在我院行腹股沟疝腹腔镜手术的小儿104例,采用随机数字表法分为丙泊酚静脉注射麻醉组与七氟烷吸入麻醉组各52例,比较两组患儿手术期不同时点的呼吸频率(RR)、心率(HR)以及两组患儿的麻醉诱导时间、苏醒时间、自主呼吸恢复时间、拔管时间、定向力恢复时间、术后躁动例数、躁动评分和不良反应。结果:观察组切皮时(T2)、麻醉后5 min(T3)的HR、RR均低于对照组,差异有统计学意义(P均<0.05)。丙泊酚组的苏醒时间、自主呼吸恢复时间、拔管时间与定向力恢复时间均长于七氟烷组(P<0.05),两组患儿的术后躁动发生率与躁动评分比较差异均无统计学意义(P>0.05);两组不良反应比较差异无统计学意义(P>0.05)。结论:丙泊酚与七氟烷均能用于小儿腹股沟疝腹腔镜手术,但七氟烷对患儿的血流动力学影响较小,苏醒质量更高。
Objective： To compare the effects and safety of propofol and sevoflurane in pediatric laparoscopic hernia. Methods： A total of 104 children accepting laparoscopic hernia from Jan. 2014 to Dec. 2016 in this hospital were selected and divided into propofol intravenous anesthesia group and sevoflurane inhalation anesthesia group according to the random number table, with 52 cases in each. The RR and HR at different time points of perioperative period, the anesthesia induction time, awaking time, spontaneous breathing recovery time, extubation time, orientation recovery time, number of postoperative agitation, agitation score and the complications of two groups were observed and compared. Results： The heart rate of T2 and T3 of observation group were significantly lower than that of control group, with statistically significant difference（ P〈0.05 ）. The awaking time, spontaneous respiration recovery time, extubation time and irectional force recovery time of propofol group were longer than those of sevoflurane group （ P〈0.05 ）. There was no significant difference between two groups in the postoperative restlessness and agitation score （ P〉0. 05 ）. There was no significant difference between two groups in the incidence of adverse reactions （P〉0.05）. Conclusion： Propofol and sevoflurane can be applied to the pediatric laparoscopic hernia, and sevoflurane has fewer influence on hemodynamics and better recovery quality.
作者
李军
Li Jun(Laohekou Women and Children＇s Hospital, Hubei Xiangyang 441800, China)
出处
《儿科药学杂志》
CAS
2018年第6期22-24,共3页
Journal of Pediatric Pharmacy
