摘要
目的:探究中西医结合治疗对蛛网膜下腔出血患者围术期迟发性血管痉挛发生的影响。方法:选取2013年8月—2015年8月医院收治的80例蛛网膜下腔出血患者作为研究对象,根据入院时间先后将患者分成观察组和对照组各40例,对照组采用常规西药治疗,观察组采用中西医结合治疗,观察并记录两组患者入院后血浆神经肽Y含量和血管痉挛指数变化情况,记录6个月内并发症发生情况,分析比较。结果:两组患者血浆神经肽Y含量变化趋势一致,在入院第3天后升至最高水平,而在第7天时明显降低,且观察组显著低于对照组患者,两组比较有统计学意义(P<0.05)。两组患者入院第1 d时血管痉挛指数较高,两组比较无统计学意义(P>0.05);而10 d后均降低,且观察组患者血管痉挛指数显著低于对照组(P<0.05)。观察组患者6个月内迟发性血管痉挛发生概率为15.00%,对照组为35.00%,显著高于观察组患者,且观察组二次出血和脑出血人数均较少,两组比较有统计学意义(P<0.05)。结论:中西医结合治疗围手术期蛛网膜下腔出血患者临床疗效好,发生迟发性血管痉挛等并发症的概率较低,有利于预后,提高患者生活质量,值得广泛推荐使用于临床当中。
Objective：To explore the effect of combined traditional Chinese and Western medicine treatment on the occurrence of delayed vasospasm in patients with subarachnoid hemorrhage.Methods：Eighty cases of patients with subarachnoid hemorrhage as the research object from August 2013 to August 2015 in our hospital,according to the chronological admission patients,were divided into observation group and control group with 40 cases in each.The control group was treated with conventional western medicine treatment and the observation group with the integrative medicine.We observed and recorded the two groups＇ hospitalized plasma neuropeptide Y content and vasospasm index changes and recorded the complications within six months.Results：Two groups＇ peptide plasma neuropeptide Y in patients with the same trend changed on 3 d after admission increasing to the highest level,but significantly lower on 7 d.And the observation group＇s was significantly lower than the control group＇s.The two groups were statistically significant（P〈0.05）.The vasospasm index was higher on 1 d of two groups＇ patients admission and the two groups were not statistically significant（P〉0.05）.And it was decreased after 10 d and the index of vasospasm in the observation group was significantly lower than the control group＇s（P〈0.05）.Patients＇ delayed vasospasm incidence within six months was 15.00% in the observation group and in the control group it was 35.00% which was significantly higher than that of the observation group.And the observation group＇s numbers of secondary hemorrhage and cerebral hemorrhage were less statistically and there was significance between the two groups significance（P〈0.05）.Conclusion：Integrative medicine has better clinical efficacy on perioperative subarachnoid hemorrhage and there is low probability of occurrence of delayed complications such as vasospasm,beneficial outcomes.And it can improve the quality of life of patients,worthy of widely use in clinic.
出处
《中华中医药学刊》
CAS
北大核心
2016年第12期2955-2957,共3页
Chinese Archives of Traditional Chinese Medicine
基金
江苏省自然科学基金项目(BK2011078)
