摘要
目的探讨儿童分化型甲状腺癌（differentiated thyroid cancer，DTC）的临床特征和治疗方法及效果。方法回顾性分析26例DTC患儿的临床资料。结果26例均以发现颈部肿块为主诉就诊；B超显示20例伴多发微小密集钙化；19例行甲状腺次全切除术，7例行甲状腺全切除术；22例有颈淋巴结转移，4例肺转移；随访37-164个月，中位随访88个月，10例有复发或转移，2例死于疾病进展；患儿5、10a总生存率分别为96．9％、71．1％，无复发生存率分别为84．3％、68．8％。结论儿童DTC具有高度侵犯特征，术后复发率较高，但病死率低，预后良好。
Objective To explore the clinical features, therapy and treatment result of differentiated thyroid cancer （DTC） in children. Methods The clinical data of 26 patients with DTC were retrospectively analyzed. Results Neck mass was the chief complaint of all patients, and ultrasound showed mutiple dense microcalcification in 20 patients. Nineteen patients underwent subtotal thyroidectomy and 7 underwent total thyroidectomy. Neck lymph node metastasis was found in 22 patients and lung metastasis in 4. The mean follow-up time was 88 （37 to 164） months. Recurrence occurred in 10 patients. Two patients died in progressive stage. The 5- and 10-year survival rates were 96. 9% and 71.1%, and recurrence-free survival rates were 84. 3% and 68. 8%. Conclusion Differentiated thyroid carcinoma in children has the features of high invasion, high recurrence rate, low fatality and fine prognosis.
出处
《中华实用诊断与治疗杂志》
2016年第5期481-482,共2页
Journal of Chinese Practical Diagnosis and Therapy
基金
河南省科技计划项目(142300410382)
关键词
甲状腺肿瘤
分化型甲状腺癌
儿童
生存
Thyroid neoplasms
differentiated thyroid cancer
children
clinical outcome
survival
