摘要
目的观察抗衰乳膏预防乳腺癌放射性皮肤损伤的临床效果。方法选取120例入院接受放射治疗的乳腺癌患者,随机分为A、B、C 3组,每组40例。放射治疗开始起A、B、C组患者照射野皮肤分别开始使用抗衰乳膏、三乙醇胺乳膏及超氧化物歧化酶(SOD)喷雾剂。对放射治疗结束后预防效果进行评价。结果治疗结束后皮肤损伤分级、严重放射性皮肤损伤(大于Ⅱ级)发生率A组与B组比较无差异(P>0.05),A组与C组比较有差异(P<0.05),A组较C组皮肤损伤轻,严重放射性皮肤损伤(大于Ⅱ级)发生率低。结论抗衰乳膏预防乳腺癌放射性皮肤损伤与三乙醇胺乳膏等效,较超氧化物歧化酶喷雾剂好,但使用抗衰乳膏性价比较高。
Objective To explore the clinical effects of Kangshuai Cream in preventing irradiation- induced dermal injury in breast cancer patients. Methods 120 patients with breast cancer who received radiotherapy were randomly divided into three groups,40 cases in each group. The patients of group A,B,C with breast cancer who initially received radiotherapy respectively used Kangshuai Cream,Triethanolamine Cream and Superoxide Dismutase( SOD) Spray. The protective effect of irradiation- induced dermal injury after radiation therapy in the three groups was evaluated. Results The degree of skin damage and serious radioactive skin lesions( > Ⅱ) in group A and group B was no difference( P > 0. 05),the degree of skin damage and serious radioactive skin lesions( > Ⅱ) in group A and group C was statistically significant( P <0. 05). The degree of skin damage and the incidence rate of severe irradiation- induced dermal injury( > Ⅱ) in group A were lower than group C. Conclusion Kangshuai Cream had same effect in preventing the irradiation- induced dermal injury in breast cancer patients,the clinical therapeutic effects of Kangshuai Cream in preventing irradiation- induced dermal injury was better than SOD Spray,and Kangshuai Cream offered better value for money.
出处
《药学研究》
CAS
2016年第2期110-111,共2页
Journal of Pharmaceutical Research
