摘要
目的了解陕西省淡水鱼中孔雀石绿的污染状况,评估陕西居民孔雀石绿的膳食暴露量,对陕西居民通过淡水鱼摄入孔雀石绿的人体健康风险进行评估。方法样品经匀浆提取后采用中性氧化铝固相萃取小柱净化,BEH C18(2.1 mm×100mm,2.5μm)色谱柱分离,利用超高效液相色谱串联质谱法进行含量测定,采用暴露边界比法对陕西省居民通过淡水鱼摄入孔雀石绿的人体健康风险进行评估。结果陕西省淡水鱼中孔雀石绿的检出率为7.32%,最大值为428μg/kg。不同品种淡水鱼中孔雀石绿的检出率差别较大,以鲶鱼中的检出率最高,为28.57%。陕西省十个地市中榆林的检出率最高,为33.33%。结论陕西省淡水鱼中残留的孔雀石绿对人体的健康风险很低,但违规使用孔雀石绿的现象比较严重,相关部门应加强对孔雀石绿的监管力度。
Objective To investigate the residue levels of malachite green（ MG） in freshwater fish and assess the dietary MG exposure of Shaanxi residents. The second aim was to assess the health risk of intaking MG from freshwater fish for Shaanxi residents.Methods The samples were determined by UPLC-MS / MS after purified by neutral alumina SPE cartridges and separated by waters-BEH C18column（ 2. 1 mm × 100 mm,2. 5μm）. The MOE method was used to assess the risk of intaking MG from freshwater fish for Shaanxi residents. Results The average detection rate of MG in freshwater fish in Shaanxi province was 7. 32% and the highest residue level was 428 μg / kg. The detection rate was quite different in different fish species. The catfish devoted the highest detection rate which was 28. 57%. In ten cities of Shaanxi,the highest detection rate was obtained from Yulin which was 33. 33%. Conclusion The health risk of intaking MG from freshwater fish is quite low for Shaanxi residents,however the contamination of illegal use of MG in freshwater fish was severe in Shaanxi Province. Supervision and inspection of MG should be strengthened in fish farming.
出处
《卫生研究》
CAS
CSCD
北大核心
2015年第6期965-969,共5页
Journal of Hygiene Research
关键词
孔雀石绿
淡水鱼
暴露评估
malachite green
freshwater fish
exposure assessment
