摘要
孔雀石绿(Malachite green,MG)是1种三苯甲烷类工业染料,曾广泛用于治疗水产动物的水霉病、烂鳃病、寄生虫病等,但由于具有高毒、高残留、“三致”等毒性性质,许多国家禁止其在经济鱼类(观赏鱼除外)的养殖过程中使用,成为药物残留监控的主要内容之一。本文对孔雀石绿的化学性质、代谢规律及机理、生物毒性等研究现状进行了综述,旨在为药残的监控工作提供理论依据。
Malachite green is an N-methylated diaminotriphenylmethane industrial dye, widely used as a strong antifungal, antibacterial, antiparasitical agent in the aquaculture industry. However, Malachite green is not approved for use in commercial fishes except for spectacular fishes in many countries, due to its high residue, high toxicity, carcinogenicity, teratogenicity, mutagenesis and so on. It is one of the key items in drug residual monitoring. This review summarizes the characteristics of malachite green and leucomalachite green, their metabolic laws and mechanisms, toxicological effects on various fish species and certain mammals. It can be of value for further monitoring of illegal use of drugs and drug residues.
出处
《中国海洋大学学报（自然科学版）》
CAS
CSCD
北大核心
2007年第1期27-32,共6页
Periodical of Ocean University of China
基金
国家科技基础平台项目(2004DEA70880)
国家科技基础公益项目(2005DIB4J049
2004DIB4J165)资助
关键词
孔雀石绿
无色孔雀石绿
代谢
生物毒性
malachite green
leucomalachite green
metabolism
bio-toxicity
