摘要
目前针对恶性肿瘤的传统治疗药物已远远不能满足临床需要。近几年抗肿瘤靶向药物的研究取得了突破性的进展,给临床治疗带来了新的希望,它具有作用于特定靶点,直接抑制肿瘤细胞的生长,减少对正常细胞和组织器官的毒副作用,可以长期用药等优点。该文旨在近几年对小分子靶向药物和抗体靶向药物的最新研究作一综述。
Traditional treatments for malignant tumor are far from meeting the clinical demands.Recently,research on anti-tumor targeted drugs has made a significant breakthrough,which brings new hope for the treatment of malignant tumor.Anti-tumor targe-ted drugs can specifically target malignant tumor and directly in-hibit the growth of tumor cells,showing no toxicity to the normal tissues and organs.Herein we reviewed the research progress of small molecular targeted drugs and antibody targeting new drugs.
出处
《中国药理学通报》
CAS
CSCD
北大核心
2015年第5期610-614,共5页
Chinese Pharmacological Bulletin
基金
国家自然科学基金资助项目(No 81373342)
北京市自然科学基金资助项目(No 2141004,7142114)
关键词
抗肿瘤
靶向治疗
药物
小分子
抗体
研究
anti-tumor
targeted therapy
drug
small mole-cule
antibody
research
