摘要
目的探讨骨关节炎患者血浆中IL-18、IL-21的水平变化及其与疾病的关系。方法通过检测26例骨关节炎患者与27例健康成人血浆中IL-18、IL-21水平的差异,探讨其与骨关节炎的关系。结果 26例骨关节炎患者血浆中IL-18和IL-21水平均高于27例健康成人,差异均有统计学意义(P<0.05)。结论 IL-18、IL-21水平在骨关节炎患者中明显增高,可能与疾病的发生有一定联系。
Objective To discuss the level changes of IL-18 and IL-21 in plasma of patients with osteoarthritis and its relationship with the disease. Methods The differences of IL-18 and IL-21 level in plasma between 26 patients with osteoarthritis and 27 healthy adults were detected to discuss the relationship with osteoarthritis. Results The levels of IL-18 and IL-21 in plasma of 26 patients with osteoarthritis were all higher than those of 27 healthy adults,the differences were all statistically significant （P〈0.05）. Conclusion The IL-18 and IL-21 levels of patients with osteoarthritis increase evidently,which has some relationship to the disease.
出处
《中国当代医药》
2013年第35期85-86,共2页
China Modern Medicine
