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血液净化方法在小儿急性中毒中的应用 被引量:13

The application of blood purification in rescuing acute poisoning in children
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摘要 目的探讨小儿急性中毒常见原因及不同血液净化方法对急性中毒的治疗效果。方法总结45例小儿急性中毒的病因、治疗方法及转归。结果45例患儿男25例,女20例,平均5.7岁。毒鼠强中毒10例,均采用血液灌流(HP),灌流次数3~7次,平均4.5次,2例患者因病情危重自动出院,8例患者好转。毒蕈中毒7例,血浆置换3例,联合血液净化4例,死亡1例,因病情危重放弃治疗3例,好转3例。百草枯中毒6例,血液灌流2~6次。死亡1例,放弃治疗1例,好转4例。1例灭多威中毒患儿死亡,余21例中毒经血液透析和(或)血液灌流治疗,好转或治愈。结论学龄前儿童是小儿急性中毒的好发年龄,中毒毒物种类繁多,以毒鼠强、毒蕈、百草枯为最多见,血液净化方法应根据毒物性质和患者情况选择最佳治疗方案,对于合并多脏器受损的患儿应及早采取联合血液净化方法。 Objective To explore the common causes of acute poisoning in children and the effects of blood purification(BP). Methods To summarize the cause and therapeutic method and prognosis of 45 cases acute poisoning in children. Results 45 cases of acute poisoning include male 25 cases and female 20 cases, average age was 5.7 years. 10 cases tetramine poisoning were cured with hemoperfusion 3-7 times,8 cases to take a turn for the better,2 cases gave up. 7 cases mushroom poisoning, 4 were treated with combined blood purification and 3 plasmapheresis ,one died,3 turu better,3 gave up.6 cases paraquat poisoning were treated with hemoperfusion,one died,one gave up,4got better. One methomyl poisoning were died.Other 21 cases were treated with hemodialysis and/or hemoperfusion ,all got better or cured. Conclusion Preschool Child was the predilection age of acute poisoning. Poisons was a great variety, tetramine, mushroom and paraquat were at most. The choose of BP methods should based on the kind of poisons and the condition of patients.The patients who had multiple organs injury should be treated with combined BP methods.
出处 《中国血液净化》 2010年第1期54-55,共2页 Chinese Journal of Blood Purification
关键词 小儿 血液净化 急性中毒 Children Blood purification Acute poisoning
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