摘要
为探讨运动及限制饮食对单纯性肥胖大鼠脂合成的影响,将大鼠随机分为四组:正常饮食对照组(ND),高脂饮食非运动组(HN),高脂饮食运动组(HE)和限制高脂饮食运动组(LE)。造肥胖模型后对HE和LE组实行游泳耐力训练,期间LE组进行限制性高脂饮食。10周后,测定其体重、体长、脂肪垫重量,并测定其肝组织乙酰CoA羧化酶(ACC)基因表达、甘油三酯、血胰岛素及极低密度脂蛋白水平。游泳训练后,HE和LE组ACC基因表达比HN组分别下降19.6%和36.3%,大鼠体重及体脂百分比也显著下降;LE组甘油三酯、血胰岛素和极低密度脂蛋白水平显著降低。且LE组甘油三酯含量比HE组显著下降。耐力训练降低了大鼠脂类的合成,结合限制饮食使这种趋势更明显,减肥效果更好。
To explore the effects of endurance training and food-restriction on fat synthesis, we divide rats into four groups randomly： Normal diet contrast group （ND）, high fat diet non-exercise group （HN）, high fat diet exercise group （HE） and high-fat diet-limiting exercise group （LE）. After making fat rats model, rats of HE and LE groups are trained to swim, and rats of LE group go on the restricted-high fat diet during this time. we measure their weight, the length of bodies, fat cushion weight, and also determine the level of acetyl CoA carboxyl enzyme （ ACC ） gene expression, triglyceride in rats liver, and the level of blood insulin, very low-density lipoprotein. 10 weeks later, ACC gene expression is 19.6% and 36.3 % in HE and LE groups lower than that in HN group, and the rats weight and body fat content decreases remarkably too. The level of liver triglyceride, blood insulin, and very low-density lipoprotein in LE group decrease remarkably. Moreover, the liver triglyceride level of LE group decreases remarkably compared with HE group. Endurance training reduces fat synthesis, and it is has a more effective function if corahined with food-restriction.
出处
《北京体育大学学报》
CSSCI
北大核心
2008年第9期1215-1218,共4页
Journal of Beijing Sport University
