摘要
目的:研究超滤膜技术应用于杜仲叶绿原酸的分离纯化。方法:以绿原酸转移率为指标,考察料液温度、超滤压力、超滤时间、膜截留分子量对绿原酸转移率的影响。结果:膜截留分子量200000,超滤温度40℃、超滤压力0.36MPa、超滤时间20min、加水量24L时,绿原酸转移率为99.38%。结论:超滤膜技术分离纯化杜仲叶绿原酸效果较好,可应用于产业化。
Objective：To isolate and purify Chlorogenic acid from Eucommia ulmoides leaves by uhrafiltration technique. Methods： Chlorogenic acid transferring ratio was investigated by temperature, pressure, time, cut-off molecular mass. Results ：The optimal conditions for the uhrafiltration technique were finally determined. It was found that, for the membrane with a cut-off molecular mass of 20000, when the temperature, pressure, time were respectively 40℃, 0. 36 MPa , 20 minutes and adding 24L water, yield of Chlorogenic acid was 99. 38%. Conclusion：High Chlorogenic acid transfering ratio can be gotten by uhrafiltration technique, which is helpful to the further isolation and purification of Chlorogenic acid in the subsequent process.
出处
《中药材》
CAS
CSCD
北大核心
2008年第4期585-588,共4页
Journal of Chinese Medicinal Materials
关键词
超滤膜技术
超滤
绿原酸
Ultrafiltration technique
Ultrafihration
Chlorogenie acid
