摘要
目的探讨尿液成分对草酸钙尿结石形成的影响。方法应用红外光谱仪对50份尿结石标本进行成分检测;对16例一水草酸钙(COM)与10例二水草酸钙(COD)尿结石患者的24 h尿液进行生化检测,并比较两组生化指标。结果87.5%的COM结石患者和90%的COD结石患者24 h尿量减少;COM结石患者尿钙(4.94±2.11)mmol/24 h,COD结石患者尿钙(9.43±3.78)mmol/24 h;差异有统计学意义(P<0.01);COM结石患者尿磷(20.50±8.76)mmol/24 h,COD结石患者尿磷(28.38±10.21)mmol/24 h,差异有统计学意义(P<0.05);87.5%的COM结石患者尿枸橼酸低于正常水平。结论COD结石患者尿钙、尿磷高于COM结石患者,表明COD结石的形成与高钙尿和高磷尿有关;COM结石的形成可能与低尿枸橼酸有关。
Objective To study the effect of urine component on calcium oxalate urine stone formation. Methods 50 urine component with urinary stones were examined by infrared spectrophotometry, from which, 16 patients with calcium oxalate monohydrate（COM） and 10 patients with calcium oxalate dehydrate（COD） were selected for the study of some urinary parameters, then the urinary parameters of two groups were compared. Results There were 41（82%） calcium oxalate urine stones. The urinary parameters in 24 h were detected. The urinary excretions of 87.5% of COM and 90% of COD group were reduced. In the COM group,the urinary calcium was （4.94±2.11）mmol/24 h whereas in the COD group it was （9.43±3.78） retool/24 h （P〈0.01）. The urinary phosphate was （28.38±10.21）mmol/24 h in the COD group whereas it was （20.50± 8.76）mmol/24 h in the COM group （P〈0.05）. The urinary sodium citrate of 87.5% COM was lower than the normal. Conclusion Urinary excretions of both calcium and phosphate were higher in the COD group. It was postulated that the formation of COD might be related to hypercalcium and hyperphosphate, whereas the formation of COM might be related to low sodium citrate in urine.
出处
《现代泌尿外科杂志》
CAS
2007年第6期366-367,共2页
Journal of Modern Urology
基金
湖南省郴州市科技局科研立项资助课题(No.05CK56-2)
湘南学院重点科研立项资助课题(No.06Z007)
关键词
尿液成分
尿结石
草酸钙
urine component
urinary stone
calcium oxalate
