摘要
研究一种基于光固化快速成形技术的人工骨支架制备方法。设计空间结构的人工骨支架负型,利用立体光固化快速成形系统制造人工骨支架负型树脂原型,在人工骨支架负型树脂原型中填充β-磷酸三钙,通过热分解的方法去除SL原型,获得生物活性人工骨支架。研究了烧结与去除原型的方法,测得人工骨支架表面粗糙度分别是Ra=3.69,有利于细胞的黏附。进行体外细胞培养研究,发现成骨细胞能够在这人工骨支架上黏附生长,并向微管内生长,具有良好的生物学特性。
The paper studies a method to fabricate the artificial bone scaffold based on the Stereolithography （SL） technology. By designing the negative resin mold of the artificial bone scaffold for the spatial structure, using SL system to make the negative resin mold for the artificial bone scaffold and fill the β-TCP into the negative resin mold of scaffold, and removing the SL prototype through pyrolysis, a bioactive artificial bone scaffold has been obtained. The approaches to sinter and remove the prototype have been studied. The surface roughness Ra of the artificial bone scaffold measured is 3.69μm, which is favorable to cellular adhesion.
出处
《机电产品开发与创新》
2006年第2期5-8,共4页
Development & Innovation of Machinery & Electrical Products
基金
国家自然科学基金资助项目(50235020)
关键词
光固化成型
骨
支架
Stereolithography
Bome
Scaffold
