摘要
为了弄清低浓度苯环境下作业人群的健康状况，对某大型石油化工企业产生低浓度苯的５个车间采集３２３个样品分析。浓度范围在０．０５～２９．２５ｍｇ／ｍ３，其中制苯车间浓度最高，均值为４．５７±６．１６ｍｇ／ｍ３；从５个车间筛选密切苯接触人群４３７人，选择非苯接触人群（对照组）１５０人，进行了外周血白细胞和淋巴细胞微核率的测定，结果表明：①外周血白细胞数虽在正常值范围之内，但非常显著低于对照组；②经常性苯接触工人淋巴细胞微核率分布高于非苯接触组，且制苯车间观察人群的淋巴细胞微核率与对照组比较，差异有显著性；③５个车间随作业环境苯浓度的增高，白细胞数有降低趋势，淋巴细胞微核率有增加的趋势。这些均证明低浓度苯对作业人群的健康有损害，尤其要注意对人体遗传物质的损伤作用。
Inordertoknowthehealthstatusinworkersexposedtolow-levelbenzene,323airsampleswerecolectedfromfiveworkshopsoftheCorporation,wherelow-levelbenzenewasemitedfromaromatichydrocarbondevices.Resultsshowedairbenzenelevelsrangedfrom0.05～29.25mg/m3,withanaverageof4.57±6.16mg/m3,andthehighestinthebenzene-producingworkshop.Fourhundredandthirty-sevenworkersclosely-exposedtobenzeneinfiveworkshopsand150controlswereselectedandtheirperipheralwhitebloodcelcountandmicronucleusoflymphocytesweredeter-mined.Resultshowedthat①peripheralwhitebloodcelcountoftheexposedworkerswaswithinthenormalrange,butobviouslylowerthanthatofthecontrols;②proportionoflymphocyticmi-cronucleuswashigherinexposedworkersthanthatinunexposedones,andtherewassignificantdif-ferenceinitbetweenworkersinbenzene-producingworkshopthanthatincontrols;③whitebloodcelcountloweredandproportionoflymphocyticmicronucleusincreasedintheworkers,withthein-creaseofairbenzenelevelinthefiveworkshops.Althesedemonstratethatlow-levelbenzeneisharmfultotheexposedworkers,especialytotheirgeneticmaterials.
出处
《中华预防医学杂志》
CAS
CSCD
北大核心
1996年第3期164-166,共3页
Chinese Journal of Preventive Medicine
关键词
苯
白细胞
外周血
淋巴细胞
微核率
BenzeneLeukocytesMicronucleuspercentageinperipherallymphocyte
