摘要
目的探索伴和不伴早醒的抑郁症病人睡眠脑电图特征。方法对10例伴早醒的抑郁症(早醒组)、8例不伴早醒的抑郁症(非早醒组)和10例对照组进行睡眠脑电图检查。结果(1)早醒组的醒起时间比对照组显著为长(11.8±8.5:3.1±2.8,P<0.05);(2)非早醒组的运动觉醒时间比对照组显著为短(3.1±1.4:6.8±3.1,P<0.05);(3)早醒和非早醒组的睡眠总时间比对照组显著为短(331.7±25.6和333.9±52.7比386.7±41.3,P均<0.05);REM强度比对照组显著为强(28.7±8.8和32.8±19.5比19.4±3.7,P均<0.05)。结论(1)抑郁症的早醒可能与精神运动性阻滞相关联;(2)不伴早醒的抑郁症可能由慢波睡眠向快波睡眠的转相增快;(3)抑郁症病人的总睡眠时间减少和REM睡眠强度增加。
Objective To explore characteristic of sleep electroencephalograph of depression pa tients with or without early awakening. Methods 10 depression patients with early awakening （early a wakening group）,8 without early awakening （non-early awakening group） and 10 patients（control group） were checked on sleep electroencephalograph. Results （1） Morning awakening time of patients in early awakening group （11. 8±8. 5） was significantly longer than that of patients in control group （3.1±2.8, P〈0.05）, （2） Movement awakening time of patients in non early awakeninggroup（3. 1±1.4） was significantly shorter than that of patients in control group（6.8±3. 1, P〈0.05）. （3） Total sleep time of patients in early awakening group and non-early awakening group（ 331. 7±25. 6 and 333. 9±52. 7） was significantly shorter than that of patients in control group（386.7±41.3, P〈0.05）. REM intensity of patients in early awakening group and non early awakening group（ 28. 7±8. 8 and 32.8±19.5） was significantly greater than that of patients in control group（ 19. 4±3. 7. P〈 0.05）. Conclusions （1）There is association of early awakening and psychomotor retardation in patients with depression; （2） It can he shifted more rapidly for phase from slow wave sleep to rapid wave sleep in pa tient with depression without early awakening; （3） In patients with depression, total sleep time is signifi cantly decreased and REM sleep intensity is significant increased.
出处
《神经疾病与精神卫生》
2005年第4期260-261,264,共3页
Journal of Neuroscience and Mental Health
基金
南京市跨世纪学科带头人后备人才专项基金资助项目(20028005)
关键词
抑郁症
早醒
睡眠脑电图
醒起时间
运动觉醒时间
Depression Early awakening Sleep electroencephalography Morning awakening time Movement awakening time
