摘要
目的 :制备复方奥硝唑含漱液 ,并建立其含量测定方法。方法 :以紫外分光光度法测定制剂中奥硝唑含量 ,以双波长等吸收点法测定醋酸氯己定含量。结果 :奥硝唑检测浓度在5 5～16 6μg/ml范围内线性关系良好 ,醋酸氯己定检测浓度在5 6～16 8μg/ml范围内线性关系良好 ,2组分的平均回收率分别为100 23 %、99 77 % ,相对标准差分别为0 47 %、0 31 %。结论 :本制剂制备和含量测定方法简便、快速、准确 ,质量可控。
OBJECTIVE:To prepare and establish the method for measuring the content of ornidazole gargle.METHODS:Maximal wavelength and dual-wavelength point spectrophotometries were used to determine the contents of ornidazole and chlorhexidine acetate respectively.RESULTS:The calibration curve of ornidazole and chlorhexidine acetate were linear in the range of5.5～16.6μg/ml and5.6～16.8μg/ml respectively.The average recovery rates of ornidazole and chlorhexidine acetate were100.23%and99.77%respectively,and their RSD were0.47%and0.31%respectively.CONCLUSION:The method of preparation and quality control is simple,quick and accurate.
出处
《中国药房》
CAS
CSCD
北大核心
2005年第5期350-351,共2页
China Pharmacy
