摘要
运用泻下与运动疲劳因素塑造大鼠脾气虚证模型。通过光镜、电镜观察和形态计量,对脾气虚证大鼠模型的骨骼肌细胞形态及肌细胞平均截面积、骨骼肌肌原纤维和线粒体体密度、线粒体面数密度进行观测。发现脾气虚与线粒体的结构异常和肌细胞的蛋白代谢负平衡相关。健脾益气的扶正健脾液对脾气虚证时的上述改变有良好的恢复作用。
In this paper, morphometric changes of skeletal muscle cells in rats withSQDS were studied based on the theory of Traditional Chinese Medicine- 'Thespleen nourishes the muscles'. Compared with the control group, it was foundthat the SQDS group's mean area of two kinds of skeletal muscle fibers and thevolume density ( Vv ) of myofibril reduced remarkably; numerical density onarea (NA) of mitochondria increased but the Vv reduced. After taking the medi-cine of 'strengthening the spleen and replenishing qi', the injury of myocyte ofthe group of 'strengthening the body resistance and the spleen' recovered appa-rently, but the control group recovered slowly. The physiological and patho-logical association between spleen and muscle was reconfirmed. It was suggestedthat the method of strengthening spleen could improve energy metabolism of themuscles.
出处
《中国运动医学杂志》
CAS
CSCD
北大核心
1993年第3期157-159,共3页
Chinese Journal of Sports Medicine
基金
国家中医药管理局资助课题
关键词
脾气虚
动物模型
骨骼肌
形态计量
morphometric study
spleenqi deficiency syndrome (SQDS)
skeletal muscle cell
rat
