摘要
目的检测生前溺死与死后抛尸的肺组织水通道蛋白的表达。方法取2种死亡方式条件下大鼠肺组织,用免疫组织化学方法检测肺组织中水通道蛋白1表达的分布特征。结果两种死亡条件下肺泡间质和支气管周围的毛细血管内皮及肺泡上皮均有AQP1的阳性表达,但积分光密度值(intergratedopticaldensity,IOD)值有显著性差别。结论AQP1在大鼠两种溺死条件下表达差别有统计学意义。
Objective To determine the expression of water channel1protein in the lung of drown rat and that of after death thrown into the water.Methods Immunohistochemical method was used and the computer image analysis was conducted to detect the distribution of AQP1.Results The positive expres-sion of AQP1was seen in the capillary endotheliocyte of the interstitial and around bronchi and in the alveolar endothelial cells.The value of intergrated optical density was statistical significant.Conclusion It suggests that AQP1is one of sensitive signs to distinguish ante-mortem and postmortem immersion.
出处
《法医学杂志》
CAS
CSCD
2004年第1期13-14,F003,共3页
Journal of Forensic Medicine
