摘要
目的 : 探讨茶多糖是否具有降低血糖、改善糖尿病症状的作用。方法 : 将四氧嘧啶导致的 型糖尿病小鼠随机分成 4组 ,每天分别灌胃给予蒸馏水、茶多糖 1 .0、2 .0、4.0 g/kgbw。每天记录饮水量 ,每周称量体重 1次 ,连续 4w,在实验中期 (2 w)、末期各测空腹血糖 1次。结果 : 茶多糖能明显缓解糖尿病小鼠“三多一少”症状 ,降低其空腹血糖 ,并存在剂量 -反应关系。同时 ,茶多糖对本实验小鼠血糖值、饮水量之间相互影响存在明显正相关性 ;饮水量与体重之间存在负相关性。结论 : 茶多糖具有降低糖尿病小鼠血糖 。
Objective: To investigate the effects of tea polysaccharide (TP) on blood glucose and diabetic symptoms in mice. Methods: Alloxan-induced diabetic mice were divided into 4 groups, and administered orally with saline, TP at doses of 1.0, 2.0, 4.0 g/kg body weight, respectively for 4 weeks. Water intake and body weight were recorded daily and weekly respectively.Fasting blood samples were collected for measurement of glucose at the end of 2nd and 4th week.Results: Symptoms of diabetic mice fed TP were improved obviously. Their blood glucose concentration and water intake decreased significantly. On the other hand, their body weight increased obviously. There was positive correlation between blood glucose and water intake, but negative correlation between water intake and body weight. Conclusion: TP can decrease blood glucose concentration and improve diabetic symptoms in mice.
出处
《营养学报》
CAS
CSCD
北大核心
2003年第3期253-255,共3页
Acta Nutrimenta Sinica
基金
浙江省医药卫生科学研究基金
关键词
茶多糖
糖尿病
血糖
四氧嘧啶
动物实验
tea polysaccharide
alloxan
diabetes
blood glucose
diabetic symptoms.
