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思他宁治疗肝硬化门静脉高压食管胃底曲张静脉破裂大出血的临床疗效观察 被引量:5

Clinic observe of Stilamin for treatment of acute bleeding from esophageal varices
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摘要 目的 观察思他宁治疗肝硬化门静脉高压食管胃底曲张静脉破裂大出血的效果,并与垂体后叶素进行比较。方法 将40例肝硬化门静脉高压食管胃底曲张静脉破裂大出血病人分为两组,分别用思他宁和垂体后叶素治疗,观察24 h止血率、总止血率、1周再出血率、1周死亡率和副反应发生率。结果 思他宁组24 h止血率和总止血率明显高于垂体后叶素组,1周再出血率、1周死亡率和副反应发生率明显低于垂体后叶素组。结论 思他宁用于治疗肝硬化门静脉高压食管胃底曲张静脉破裂大出血,止血效果确切,副作用少,明显优于垂体后叶素。 Objective To observe the effect of Stilamin for treatment of acute bleeding from esophageal varices and to compare with pituitrin. Methods Of 40 patients with acute bleeding from esophageal varices, 20 were treated using Stilamin and another 20 using pituitrin. The rates of hemostais within 24 h and 72 h, the rates of repeated bleeding, motality rates and occurrent of side effect were recorded. Results In stilamin group, the rates of hemostais within 24 h and 72 h were higher and the rates of repeated bleeding, motality rates and occurrent of side effect were lower than in pituitrin group. Conclusions Stilamin is more effective in treatment of acute bleeding from esophageal varices than pituitrin.
出处 《临床外科杂志》 2003年第5期311-312,共2页 Journal of Clinical Surgery
关键词 思他宁 肝硬化门静脉高压 食管胃底曲张静脉破裂 Stilamin acute bleeding esophageal varices
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  • 1李之印,徐德征,薛观臻,张秋玲.施他宁和硬化剂治疗门脉高压食管静脉曲张破裂出血[J].肝胆胰外科杂志,1997,9(4):170-171. 被引量:1
  • 2Mccormick PA, Dick R, Siringo S, et al. Octreotide reduces azygous blood flow in cirrhotic patients with portal hypertension[J]. EurJ Gastroenteral Hepatol, 1990, 2:489-492.
  • 3Planas R, Quer JC, Boix J, et al. A prospective randomized trial comparing somatostatin and sclerotherapy in the treatment of acute variceal bleeding[J]. Hepatology, 1994, 20 : 370-374.

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