摘要
目的探讨施他宁(生长抑素)联合奥美拉唑治疗肝硬化合并上消化道大出血的疗效。方法将确诊的83例患者随机分为三组。治疗组采用施他宁联合奥美拉唑的治疗方案,对照1组采用奥曲肽联合奥美拉唑的方案,对照2组采用垂体后叶素联合奥美拉唑的方案,观察时间为72 h。结果治疗组、对照1组、对照2组的止血有效率分别为93.3%、68.0%、57.1%,治疗组的止血有效率明显高于两个对照组(P<0.05);治疗组、对照1组、对照2组的有效止血时间分别为(29.71±6.35)h,(38.24±7.04)h,(40.88±9.98)h,治疗组的有效止血时间明显短于两个对照组(P<0.01)。结论施他宁联合奥美拉唑治疗肝硬化合并上消化道大出血疗效满意。
Objective To study the therapeutic effect of stilamin （somatostatin） combined with omeprazole on cirrhosis of liver complicated with massive haemorrhage from upper digestive tract. Methods All the 83 patients with cirrhosis of liver complicated with massive haemorrhage from upper digestive tract were devided into three groups at random. The treatment group was treated with the plan of stilamin plus omcprazole, Control Group A with sandostatin plus omeprazole, and Control Group B with pituitrin plus omeprazole for 72 hours. Results The treatment group＇s efficiency of bleeding-arrest was 93.3%, significantly higher than that of Control Group A （ 68.0% ） or Control Group B （ 57. 1% ） （ P 〈 0.05 ）. Their effective bleeding-arrest time was respectively 29.71 ± 6.35, 38.24±7.04 and 40.88±9, 98 （ h）, among which the first one was significantly higher than the others （ P 〈 0.01 ）. Conclusion It is satisfying that stilamin plus omeprazole is applied to cirrhosis of liver complilcated with massive haemorrhage for treatment.
出处
《临床军医杂志》
CAS
2006年第2期159-160,共2页
Clinical Journal of Medical Officers
关键词
生长抑素
奥美拉唑
肝硬化
上消化道大出血
somatostatin
omeprazole
hepatocirrhosis
massive haemorrhage
upper digestive tract
