摘要
目的观察基于经络理论指导的电刺激止痛穴位治疗肛肠疾病术后疼痛的疗效及相关炎性因子水平的变化。方法采用随机数字表法将120例符合纳入标准的肛门病术后疼痛患者随机分为研究组和对照组,对照组60例受试者术后遵医嘱采用镇痛类药物治疗,研究组60例采用电针治疗联合镇痛类药物治疗,比较两组患者在术后治疗前及治疗后疼痛缓解情况及炎症因子白细胞介素-6(Interleukin-6,IL-6)和肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)水平的变化。电刺激治疗采取腧穴分别为长强、秩边、承山、束骨、支沟和合谷,观察期为7 d。结果在术后疼痛治疗前和治疗后8 h和12 h,对照组与研究组疼痛强度差异无统计学意义(P>0.05)。在疼痛治疗后24 h时,对照组与研究组的镇痛效果差异有统计学意义(P<0.05),在疼痛治疗后48 h和首次排便时,研究组镇痛效果明显优于对照组,差异有统计学意义(P<0.05)。在疼痛治疗后7 d,两组患者疼痛评分相近(P>0.05)。与对照组相比,研究组患者IL-6和TNF-α水平在治疗前和治疗后第1天未见下降趋势(P>0.05);在第3、7天时间点IL-6显著下降并高于对照组(P<0.05);在第3天时,研究组患者TNF-α显著下降(P<0.05),7 d时仍有下降趋势,但与对照组相比差异无统计学意义(P>0.05)。结论经络理论指导下电刺激治疗联合口服镇痛类药物对肛门病术后疼痛具有较好疗效,可有效减轻排便时疼痛感,并显著降低炎性因子含量,对肛门病术后疼痛治疗具有积极作用。
Objective To observe the therapeutic effect and the levels of related inflammatory factors of electrical stimulation pain-relieving acupoints guided by meridian theory in the treatment of postoperative pain in anal and intestinal diseases.Method A hundred and twenty patients with postoperative pain of anal diseases who met the inclusion criteria were randomly divided into a study group and a control group by using a random number table method.The control group consisted of 60 patients who followed the doctor's instructions to receive analgesics after surgery,while the study group consisted of 60 patients who received electroacupuncture combined with analgesics.The pain relief,the levels of inflammatory factors interleukin-6(IL-6)and tumor necrosis factor-α(TNF-α)were compared between the two groups before and after surgery.The acupoints used for electrical stimulation therapy were Changqiang(DU1),Zhibian(BL54),Chengshan(BL57),Shugu(BL65),Zhigou(SJ6)and Hegu(LI4),with an observation period of 7 days.Results There was no significant difference in pain intensity between the control group and the study group before and 8 and 12 hours after postoperative pain treatment(P>0.05).At 24 hours after pain treatment,there was no significant difference in the analgesic effect between the control group and the study group(P>0.05).At 48 hours after pain treatment and the first bowel movement,the analgesic effect of the study group was significantly better than that of the control group,with a statistically significant difference(P<0.05).After 7 days of pain treatment,the pain scores of the two groups of patients were similar(P>0.05).Compared with those of the control group,the levels of IL-6 and TNF-αof the study group showed no downward trend before treatment and on the first day after treatment(P>0.05).At the 3rd and 7th day time points,the level of IL-6 significantly decreased and was higher than that of the control group(P<0.05).On the 3rd day,the level of TNF-αin the study group had a significant decrease(P<0.05),and there was still a downward trend after 7 days,but there was no significant difference compared to that in the control group(P>0.05).Conclusion Under the guidance of meridian theory,electrical stimulation therapy combined with oral analgesics has a good therapeutic effect on postoperative pain of anal diseases,and can effectively alleviate pain during defecation,and significantly reduce the content of inflammatory factors.It has a positive effect on postoperative pain treatment of anal diseases.
作者
刘剑
王春晓
刘德龙
袁和学
曹丹
陈萌
于永铎
殷志韬
LIU Jian;WANG Chunxiao;LIU Delong;YUAN Hexue;CAO Dan;CHEN Meng;YU Yongduo;YIN Zhitao(Shenyang Anorectal Hospital,Shenyang 110002,Liaoning,China;The Third Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110005,Liaoning,China;The Second Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110034,Liaoning,China)
出处
《中华中医药学刊》
北大核心
2025年第2期92-95,共4页
Chinese Archives of Traditional Chinese Medicine
基金
国家自然科学基金青年科学基金项目(81804094)
辽宁省“兴辽英才计划”项目(XLYC2002002)
沈阳市科学技术计划项目(22-321-33-80)
沈阳市卫健委科研项目(2022090)。
关键词
电刺激
肛门病
术后疼痛
electrical stimulation
anal disease
postoperative pain
