摘要
合成生物学是一门将工程与科学相结合的新兴交叉学科。合成生物学可以改造或创造生物体,正在为许多领域带来巨大的变化,并帮助应对医学、农业、制造业和环境方面的挑战,为人类带来巨大的利益。然而,作为一门两用学科,由于其复杂性和不确定性的特点,合成生物学也存在潜在的生物安全和生物安保风险,给生物安全管理带来一定困难。本文描述了合成生物学的发展现状及其引发的亟需解决的生物安全问题,阐述风险评估在合成生物学研发活动生物安全管理中的重要性,进而首次提出合成生物学研发活动的生物风险分类分级管理的思路及相关的针对性建议。
Synthetic biology is an emerging interdisciplinary discipline that combines engineering and science.Synthetic biology,which can modify or create living organisms,is making a huge difference in many fields and helping to address challenges in medicine,agriculture,manufacturing,and the environment for the great benefit of humankind.However,as a dual-use discipline,synthetic biology is also characterized by potential biosafety and biosecurity risks due to its complexity and uncertainty,making it difficult to biosafety management.The article describes the rapid development of synthetic biology and the urgent biosafety issues it raises,explains the importance of risk assessment in the biosafety management of synthetic biology R&D activities,and then proposes for the first time the idea of categorizing and hierarchical management of the biological risks of synthetic biology R&D activities and related targeted recommendations.
作者
黄翠
宋冬林
梁慧刚
HUANG Cui;SONG Donglin;LIANG Huigang
出处
《中国医药生物技术》
2025年第1期13-18,共6页
Chinese Medicinal Biotechnology
基金
国家重点研发计划(2020YFA0908603)。
