摘要
目的探讨布地奈德雾化吸入联合阿奇霉素序贯治疗对于肺炎支原体肺炎(MPP)患儿的影响。方法选取2022年8月—2023年3月烟台市莱阳中心医院收治的416例MPP患儿为研究对象,按随机数字表法将其分为对照组与观察组,各208例。对照组采用阿奇霉素序贯治疗,观察组在对照组基础上联合布地奈德雾化吸入治疗。对比两组患者的临床疗效、肺功能指标及不良反应发生情况。结果观察组治疗总有效率为94.23%,高于对照组的82.69%,差异有统计学意义(P<0.05)。治疗后,观察组用力肺活量、第1秒用力呼气容积均大于对照组,最大呼气流量快于对照组,组间差异有统计学意义(P<0.05)。两组不良反应发生率对比,差异无统计学意义(P>0.05)。结论布地奈德雾化吸入联合阿奇霉素序贯治疗对MPP患儿临床效果显著,能够使肺功能得到改善,且安全性良好。
Objective To investigate the effect of budesonide hebulized inhalation combined with sequential treatment with azithromycin on children with mycoplasma peumoniae pneumonia(MPP).Methods A total of 416 children with MPP admitted to Laiyang Central Hospital of Yantai City from August 2022 to March 2023 were selected as the research objects,and were divided into a control group and an observation group according to random number table method,with 208 cases in each group.The control group received sequential treatment with azithromycin,and the observation group received combined treatment with budesonide nebulized inhalation on the basis of the control group.The clinical efficacy,pulmonary function indicators and the occurrence of adverse reactions were compared between the two groups.Results The total effective rate of the observation group was 94.23%,which was higher than 82.69% of the control group,and the difference was statistically significant(P<0.05).After treatment,the forced vital capacity and forced expiratory volume at the first second in the observation group were higher than those in the control group,and the maximum expiratory flow rate was faster than that in the control group,with statistical significance(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The budesonide nebulized inhalation combined with sequential treatment with azithromycin has significant clinical effect on MPP children,and can improve lung function with good safety.
作者
王新燕
宫凯
WANG Xinyan;GONG Kai(Department of Pediatric Internal Medicine,Laiyang Central Hospital,Yantai City,Yantai 265200,China;Medical Imaging Teaching and Research Office,Laiyang Health School,Shandong Province,Laiyang 265200,China)
出处
《反射疗法与康复医学》
2024年第14期100-103,共4页
Reflexology And Rehabilitation Medicine
关键词
肺炎支原体肺炎
布地奈德
阿奇霉素序贯治疗
临床疗效
Mycoplasma pneumoniae pneumonia
Budesonide
Sequential treatment with azithromycin
Clinical efficacy
