摘要
目的探讨基于分层评估的药学延伸服务在慢性阻塞性肺疾病(COPD)老年患者中的应用效果。方法选取2022年1月至12月的九江市第三人民医院收治的74例COPD患者作为研究对象,采用随机数字表法将其分为对照组(37例)与观察组(37例)。对照组采用常规用药指导,观察组采用基于分层评估的药学延伸服务。比较两组用药依从性、肺功能指标、急性加重次数、临床有效控制率和不良反应。结果观察组用药剂量正确率、用药时间正确率高于对照组,干预3、6个月后用力肺活量(FVC)、第1秒用力呼气量占预计值百分比(FEV1%pred)、每分钟最大通气量占预计值百分比(MVV%pred)高于对照组,1年内COPD急性加重次数少于对照组,差异有统计学意义(P<0.05)。观察组临床有效控制率高于对照组,不良反应总发生率低于对照组,差异有统计学意义(P<0.05)。结论COPD老年患者采用基于分层评估的药学延伸服务可提高临床有效控制率及用药依从性,且不良反应少,可改善肺功能,降低急性加重次数。
Objective To explore the application effect of pharmaceutical extension services based on hierarchical evaluation in elderly patients with chronic obstructive pulmonary disease(COPD).Methods A total of 74 COPD patients admitted to the Jiujiang Third People's Hospital from January to December 2022 were selected as the study objects,and they were divided into control group(37 cases)and observation group(37 cases)by random number table method.The control group was given routine medication guidance,and the observation group was given pharmaceutical extension service based on stratified evaluation.The medication compliance,pulmonary function index,number of acute exacerbations,clinical effective control rate and adverse reactions were compared between the two groups.Results The dose accuracy and time accuracy of the observation group were higher than those of the control group,the forced vital capacity(FVC),the forced expiratory volume in the first second to the predicted value(FEV1%pred)and the maximum volume per minute to the predicted value(MVV%pred)after 3 and 6 months of intervention were higher than those of the control group,and the number of COPD acute exacerbations within 1 year was lower than that of the control group,the differences were statistically significant(P<0.05).The clinical effective control rate of the observation group was higher than that of the control group,and the total incidence of adverse reactions was lower than that of the control group,with statistical significances(P<0.05).Conclusion The use of pharmaceutical extension services based on stratified evaluation in elderly COPD patients can improve clinical effective control rate and medication compliance,with fewer adverse reactions,improve lung function,and reduce the number of acute exacerbations.
作者
周欢
吕佩芳
ZHOU Huan;LYU Peifang(Department of Pharmacy,Jiujiang Third People's Hospital,Jiangxi Province,Jiujiang 332000,China)
出处
《中国当代医药》
CAS
2024年第30期105-108,112,共5页
China Modern Medicine
基金
江西省卫生健康委科技计划项目(202410627)。
关键词
慢性阻塞性肺疾病老年患者
分层评估
药学延伸服务
常规用药指导
用药依从性
不良反应
Elderly patients with chronic obstructive pulmonary disease
Layered evaluation
Pharmaceutical extension services
Routine medication guidance
Medication compliance
Adverse reactions
