摘要
目的探讨儿科临床中阿奇霉素用药不良反应和临床药学作用。方法选取2020年6月—2023年6月本院收治的80例儿科临床患儿,并将其按照治疗方法的不同分为研究组和对照组,每组40例。其中,对照组应用常规对症治疗,研究组在对照组治疗基础上加用阿奇霉素进行治疗,对两组治疗总有效率、药物所引发的不良反应率以及治疗满意度进行比较分析。结果研究组总有效率与对照组基本相同,差异无统计学意义(P>0.05)。研究组不良反应发生率低于对照组,差异有统计学意义(P<0.05)。在治疗4个月后,研究组满意度与对照组相比基本相同,差异无统计学意义(P>0.05)。结论在儿科临床用药实践中,阿奇霉素的过度使用往往容易诱发药物不良反应,这不仅影响了患儿的康复效果,还可能导致家属对治疗过程的不满。因此,在儿科临床工作中,医生必须准确掌握阿奇霉素的正确使用方法、剂量范围,并加强对该药物的药学分析与评估,以确保用药的合理性,从而有效减少不良反应的发生,提升患儿的治疗效果,提高家属的满意度。
Objective To explore presentation of adverse drug reactions after application of azithromycin in pediatric clinical practice from clinical pharmaceutical perspective.Methods The paper chose 80 pediatric patients in our hospital with inclusion and exclusion criteria from June 2020 to June 2023 for study,and divided them into two groups according to different treatment methods.40 cases in control group were treated with routine symptomatic treatment,while 40 cases in study group with azithromycin treatment.Total effective rate of treatment,adverse reaction rate,and treatment satisfaction degree was evaluated and compared between two groups.Results Total effective rate of study group treated with azithromycin was basically the same as control group treated with routine symptomatic therapy,there was no significant statistical deviation(P>0.05).Adverse reaction rate of drugs in study group was significantly higher than control group(P<0.05).Treatment satisfaction degree after 4 months of treatment in study group treated with azithromycin was similar to control group treated with routine symptomatic therapy,there was no significant statistical difference(P>0.05).Conclusion Research shows azithromycin is highly likely to cause adverse drug reactions in pediatric clinical medication,which is not conducive to recovery of patient,family members of patients are not satisfied with frequent application of the drug during treatment process.Therefore,it is necessary to have clear understanding of specific usage method and dosage of azithromycin,and strengthen pharmaceutical analysis of azithromycin of hospitalized children during pediatric clinical practice,to achieve rational medication and reduce incidence of adverse reactions.
作者
邢树镇
刘汉嘉
XING Shuzhen;LIU Hanjia(Chaozhou Central Hospital,Chaozhou,Guangdong 521000)
出处
《智慧健康》
2024年第12期118-120,共3页
Smart Healthcare
关键词
阿奇霉素
儿科临床
不良反应
药学研究
治疗有效率
Azithromycin
Pediatric clinical practice
Adverse reactions
Pharmaceutical research
Treatment effectiveness
