摘要
磁共振波谱(magnetic resonance spectroscopy,MRS)将磁共振数据应用于测定分子结构的谱学技术,为中医药领域的机制研究和发展提供了创新性的研究手段,有助于深化对中医药理论的现代化理解,推动中医药学科的持续发展。通过MRS技术可以探测脑内代谢物及体外鉴定体液或组织中存在的未知化合物,揭示中医药手段干预下的脑中枢机制。本研究聚焦于MRS技术概述、MRS技术与中医药领域结合的优势、MRS技术在中医药领域的应用研究现状等方面进行总结,并探讨MRS技术在中医药领域应用的既往研究空白与缺陷,以期为研究者提供有益参考。
Magnetic resonance spectroscopy(MRS),a spectroscopic technique that applies magnetic resonance data to the determination of molecular structure,provides an innovative research tool for the study and development of mechanisms in the field of traditional Chinese medicine(TCM),which helps to deepen the modern understanding of TCM theories and promotes the continued development of the TCM discipline.The MRS technique allows the detection of metabolites in the brain and the in vitro identification of unknown compounds present in body fluids or tissues,revealing the central brain mechanisms under the intervention of TCM tools.This study focused on the overview of MRS technology,the advantages of combining MRS technology with the field of Chinese medicine,the current status of research on the application of MRS technology in the field of Chinese medicine to summarise,and to explore the gaps and shortcomings in the previous research on the application of MRS technology in the field of Chinese medicine,with a view to providing useful references for researchers.
作者
吴双
吕智桢
周星辰
利涛
洪泽
孙佳雨
吕立江
WU Shuang;LYU Zhizhen;ZHOU Xingchen;LI Tao;HONG Ze;SUN Jiayu;LÜLijiang(Department of Tuina,the Third Affiliated Hospital of Zhejiang Chinese Medical University(Zhongshan Hospital of Zhejiang Province),Hangzhou 310005,China;The Third School of Clinical Medicine,Zhejiang Chinese Medical University,Hangzhou 310053,China)
出处
《磁共振成像》
CAS
CSCD
北大核心
2024年第4期229-234,共6页
Chinese Journal of Magnetic Resonance Imaging
基金
国家自然科学基金项目(编号:82274672)
浙江省“尖兵”“领雁”重大研发攻关项目(编号:2022C03123)
浙江省吕立江名老中医专家传承工作室建设项目(编号:GZS2021026)
国家中医药管理局高水平中医药重点学科项目(编号:GJXK2023-85)。
关键词
磁共振波谱
中医药
应用研究
作用机制
磁共振成像
脑代谢
magnetic resonance spectroscopy
traditional Chinese medicine
applied research
action mechanism
magnetic resonance imaging
cerebral metabolism
