摘要
目的 探讨老年高血压患者合并阻塞性睡眠呼吸暂停低通气综合征(OSAHS)对血压水平及心功能的影响。方法 选取2020年8月至2022年8月郑州大学第一附属医院收治的92例老年高血压患者为研究对象。所有患者经多导睡眠呼吸监测,根据呼吸暂停低通气指数分为单纯高血压组(n=44)与高血压合并OSAHS组(n=48)。比较两组日间和夜间的动态血压水平及24 h平均血压水平;使用多普勒彩色超声检测两组心功能,其检测指标包括右心室舒张期内径(RVIDd)、室间隔厚度(IVSTd)、肺动脉环径(PA)、二尖瓣舒张早期最大充盈速度(E峰)、二尖瓣舒张晚期最大充盈速度(A峰)、E峰与A峰比值、左心室射血分数(LVEF),比较两组心功能指标。结果 高血压合并OSAHS组的日间血压和夜间血压均显著高于单纯高血压组,差异有统计学意义(P<0.05)。高血压合并OSAHS组的24 h平均收缩压和24 h平均舒张压均比单纯高血压组高,差异均有统计学意义(P<0.05)。高血压合并OSAHS组的RVIDd、IVSTd、PA及A峰大于单纯高血压组,差异有统计学意义(P<0.05);高血压合并OSAHS组的E峰、E/A及LVEF都小于单纯高血压组,差异有统计学意义(P<0.05)。讨论 老年高血压患者合并OSAHS不仅可明显升高患者的血压水平,还可导致患者心功能降低。
of Zhengzhou University;Objective To investigate the effect of obstructive sleep apnea-hypopnea syndrome(OSAHS) on blood pressure and cardiac function in elderly hypertensive patients. Methods Ninety-two elderly hypertensive patients admitted to the First Affiliated Hospital of Zhengzhou University from August 2020 to August 2022 were selected as the research subjects. All patients were divided into simple hypertension group(n=44) and hypertension combined with OSAHS group(n=48) based on the apnea hypopnea index through multi-channel sleep breathing monitoring. The daytime and nighttime ambulatory blood pressure levels and 24-hour average blood pressure levels between the two groups were compared. Using Doppler color ultrasound to detect the cardiac function, including right ventricular diastolic diameter(RVIDd), interventricular septal thickness(IVSTd), pulmonary artery diameter(PA), early mitral valve filling velocity(E-peak), late mitral valve filling velocity(A-peak), ratio of E-peak to A-peak, left ventricular ejection fraction(LVEF), and the cardiac function indicators between the two groups were compared. Results The daytime blood pressure and nighttime blood pressure of the hypertension combined with OSAHS group were significantly higher than those of the simple hypertension group, and the differences were significant(P<0.05).The 24-hour mean systolic blood pressure and 24-hour mean diastolic blood pressure of the hypertension combined with OSAHS group were higher than those of the simple hypertension group, and the differences were significant(P<0.05).The RVIDd, IVSTd, PA, and A peaks in the hypertension combined with OSAHS group were significantly higher than those in the simple hypertension group(P<0.05). The E peak, E/A, and LVEF of the hypertension combined with OSAHS group were smaller than those of the simple hypertension group, with significant differences(P<0.05). Conclusions OSAHS in elderly hypertensive patients not only causes a significant increase in blood pressure, but also leads to reduced cardiac function.
作者
张莹
杨亚萍
曹丽俐
Zhang Ying;Yang Yaping;Cao Lili(Department of Throroat,Head and Nech Surgery,the First Afiliated Hospital of Zhengzhou University,Zhengzhou 450000,China)
出处
《临床医学》
2023年第12期1-4,共4页
Clinical Medicine
