摘要
目的探讨脑卒中后昼间嗜睡(EDS)与患者睡眠呼吸障碍的相关性。方法148例脑卒中患者依据Epworth嗜睡量表(ESS)分为EDS组(ESS>7分)69例和非EDS组(ESS≤7分)79例。比较2组患者的一般资料、血液生化及多导睡眠呼吸监测(PSG)相关指标,Spearman相关分析脑卒中后EDS与SDB发病率的相关性,二元多因素Logistic回归分析脑卒中后EDS的影响因素。结果EDS组男性比例、低通气指数(AHI)、氧减指数(ODI)、N1睡眠期比例、夜间平均舒张压高于非EDS组(P<0.05);卒中患者EDS和SDB的发病呈正相关性(rs=0.225,P<0.05);二元多因素Logistic回归分析结果显示,男性(OR=2.768,95%CI:1.133~6.765)、高AHI值(OR=1.048,95%CI:1.023~1.074)和夜间平均舒张压升高(OR=1.035,95%CI:1.001~1.071)是卒中后EDS的独立危险因素。结论男性、高AHI及夜间平均舒张压升高是脑卒中后EDS的独立危险因素。
Objective To explore the correlation between excessive daytime sleepiness(EDS)and sleep disordered breathing after stroke.Methods A total of 148 patients with stroke were divided into the EDS group(ESS>7,n=69)and the non-EDS group(ESS≤7,n=79)according to Epworth Sleepiness Scale(ESS).The general data,blood biochemistry and polysomnography(PSG)parameters were compared between the two groups of patients.The correlation between EDS and SDB incidence rate after stroke was analyzed by spearman test.Multivariate Logistic regression analysis was applied for influencing factors of EDS after stroke.Results There were higher proportion of males,hypoventilation index(AHI),oxygen reduction index(ODI),proportion of N1 sleep period and average nighttime diastolic blood pressure in the EDS group than those of the non-EDS group(P<0.05).There was a positive correlation between the incidence rate of EDS and SDB in stroke patients(rs=0.225,P<0.05).Multivariate Logistic regression analysis revealed that gender(OR=2.768,95%CI:1.133-6.765),high AHI(OR=1.048,95%CI:1.023-1.074)and high average nighttime diastolic blood pressure(OR=1.035,95%CI:1.001-1.071)were the independent risk factors for EDS after stroke.Conclusion Male,higher AHI and high average nighttime diastolic blood pressure are independent risk factors for EDS after stroke.
作者
王文熠
陈光
WANG Wenyi;CHEN Guang(First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,National Clinical Research Center for Chinese Medicine Acupuncture and Moxibusion,Tianjin 300381,China)
出处
《天津医药》
CAS
北大核心
2023年第12期1369-1373,共5页
Tianjin Medical Journal
基金
天津市教委科研计划项目(2022KJ172)。
关键词
脑卒中
睡眠呼吸暂停综合征
影响因素
昼间嗜睡
多导睡眠呼吸监测
stroke
sleep apnea syndromes
root cause
sleepiness during the day
multichannel sleep breathing monitoring
