摘要
目的观察苯磺贝他斯汀片联合玉屏风颗粒治疗慢性荨麻疹的临床疗效。方法选取2019年6月—2021年6月于南丰县疾病预防控制中心门诊部就诊的72例慢性荨麻疹患者,按治疗方式分为治疗组和对照组,各36例。对照组采用苯磺贝他斯汀片治疗,治疗组采用苯磺贝他斯汀片联合玉屏风颗粒治疗,疗程均为12周。比较2组患者的治疗效果、不良反应和复发情况。结果治疗8周及12周时2组患者的症状积分下降较明显,治疗组症状积分均明显低于对照组,差异均有统计学意义(P<0.05)。疗程结束后治疗组治疗总有效率为94.44%,高于对照组的72.22%,差异有统计学意义(P<0.05)。2组患者在治疗过程中均未出现严重不良反应。疗程结束时随访,治疗组慢性荨麻疹复发率为14.71%,明显低于对照组61.54%,差异有统计学意义(P<0.05)。结论运用苯磺贝他斯汀片联合玉屏风颗粒治疗慢性荨麻疹,临床疗效显著,复发率低,安全性较好。
Objective To observe the clinical effect of Betahistine besilate tablets with Yupingfeng granule combined in the treatment of chronic urticaria.Methods A total of 72 patients with chronic urticaria who visited the outpatient department of Nanfeng County Center for Disease Control and Prevention from June 2019 to June 2021 were selected and divided into treatment group and control group according to the research method,with 36 cases in each group.The control group was treated with Betahistine besilate tablets,and the treatment group was treated with Betahistine besilate tablets combined with Yupingfeng granule.The course of treatment was 12 weeks.The therapeutic effect,adverse reaction and recurrence of the two groups were observed.Results After 8 and 12 weeks of treatment,the symptom scores in the treatment group were significantly lower than those in the control group(P<0.05).After the end of the treatment course,the total effective rate of the treatment group was 94.44%,compared with 72.22%in the control group,significant difference was observed between two groups(P<0.05).There were no serious adverse reactions during treatment in two groups.At the end of treatment course,the recurrence rate of chronic urticaria in the treatment group was 14.71%,significantly lower than 61.54%in the control group,and the difference was statistically significant(P<0.05).Conclusion Betahistine besilate tablets with Yupingfeng granule combined in the treatment of chronic urticaria have significant clinical effect,low recurrence rate and good safety.
作者
付兰红
黄贵义
Fu Lanhong;Huang Guiyi(Nanfeng County Center for Disease Control and Prevention,Fuzhou,Jiangxi 344500)
出处
《基层医学论坛》
2023年第34期125-127,共3页
The Medical Forum
关键词
苯磺贝他斯汀片
玉屏风颗粒
慢性荨麻疹
Betahistine besilate tablets
Yupingfeng granule
Chronic urticaria
