摘要
目的:探讨支气管镜检查联合支气管肺泡灌洗在儿童慢性湿性咳嗽中的应用效果,为临床诊治提供参考。方法:选取2021年10月—2022年8月于清远市妇幼保健院儿童呼吸科住院的患儿120例为研究对象,采用随机分组法分为支气管镜组和对照组,各60例。对照组给予常规的慢性湿性咳嗽检查和治疗,支气管镜组在对照组基础上行支气管镜检查及支气管肺泡灌洗。记录支气管镜组手术前后诊断一致率、漏诊率、误诊率,以及两组并发症发生率,对比两组住院时间、住院费用、咳嗽症状评分、临床治疗总有效率、慢性湿性咳嗽复发率。结果:支气管镜组术前与术后诊断诊断一致率26.67%,漏诊率30.00%,误诊率43.33%。两组术后无并发症发生。支气管镜组患儿住院时间、住院费用高于对照组,差异有统计学意义(P<0.05);两组患儿咳嗽评分比较,差异无统计学意义(P>0.05)。两组患儿临床治疗总有效率比较,差异无统计学意义(P>0.05);支气管镜组半年后慢性湿性咳嗽复发率低于对照组,差异有统计学意义(P=0.029)。结论:支气管镜联合肺泡灌洗能够降低慢性湿性咳嗽复发率,安全性较高,特别对于病程长、常规治疗效果不好的慢性湿性咳嗽或复发者需及时完善支气管镜检查。
Objective:To explore the effect of bronchoscopy combined with bronchoalveolar lavage in chronic wet cough in children,and to provide reference for clinical diagnosis and treatment.Methods:A total of 120 children hospitalized in the Department of Children's Respiratory,Qingyuan Maternal and Child Health Hospital were selected as the study objects from October 2021 to August 2022,and were randomly divided into bronchoscopy group and control group,with 60 cases in each group.The control group received routine examination and treatment of chronic wet cough,and the bronchoscopy group received basal bronchoscopy and bronchoalveolar lavage on the basis of the control group.The diagnostic consistency rate,missed diagnosis rate,misdiagnosis rate and complication rate of the two groups were recorded in the bronchoscopy group before and after operation,and the hospitalization time,hospitalization expenses,cough symptom score,total clinical treatment effective rate and recurrence rate of chronic wet cough were compared between the two groups.Results:In the bronchoscopy group,the diagnostic consistency rate between preoperative and postoperative diagnosis was 26.67%,the missed diagnosis rate was 30.00%,and the misdiagnosis rate was 43.33%.There were no postoperative complications in both groups.The hospitalization time and hospitalization expenses of the children in the bronchoscopy group were higher than those of the control group,and the difference was statistically significant(P<0.05);there was no statistically significant difference in cough scores between the two groups(P>0.05).There was no significant difference in the total effective rate of clinical treatment between the two groups(P>0.05);the recurrence rate of chronic wet cough in the bronchoscopy group after half a year was lower than that of the control group,and the difference was statistically significant(P=0.029).Conclusion:Bronchoscopy combined with alveolar lavage can reduce the recurrence rate of chronic wet cough with high safety,especially for patients with chronic wet cough or recurrence with long course of disease and poor effect of conventional treatment,bronchoscopy should be improved in time.
作者
米沛明
潘杰文
黄家宜
戴洪法
Mi Peiming;Pan Jiewen;Huang Jiayi;Dai Hongfa(Department of Children's Respiratory,Qingyuan Maternal and Child Health Hospital,Qingyuan 511500,Guangdong Province,China)
出处
《中外医药研究》
2023年第20期144-146,共3页
JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH
基金
清远市科技立项项目(编号:211125104560581)。
