摘要
功能性消化不良(FD)是消化系统常见疾病,其病势绵长、难以根治,对患者日常生活产生严重影响。FD胃肠动力障碍、肠道菌群失调、线粒体功能紊乱等发病机制与中医学脾虚后脾胃升降失司、肠道传送失职等观点相契合。本文从“脾虚”与FD的致病机制关联性入手,将“脾主肌肉”“脾主运化”“脾为后天之本”与FD关键病机相结合进行论述,深入探讨脾脏在FD发生发展及治疗过程中的重要性,为中医药治疗FD提供理论依据。
Functional dyspepsia(FD)is a common functional disease of digestive system,which is long and difficult to cure,with a serious impact on the daily life of FD patients.The pathogenic mechanisms of FD,such as gastrointestinal motility disorder,intestinal flora disorder,mitochondrial function dysfunction,etc.,are consistent with the views of“spleen deficiency”in TCM,such as the imbalance of qi movement of spleen and stomach and dysregulation of intestinal transmission.Starting from the correlation between“spleen deficiency”in TCM and the pathogenic mechanism of FD,this article systematically discussed the key pathogenesis of FD with the combination of“spleen governing muscles”,“spleen governing transportation and transformation”and“spleen being acquired foundation”in the basic theories of TCM,and further discussed the importance of spleen in the occurrence,development and treatment of FD,providing theoretical basics for TCM treatment of FD.
作者
李淑婷
杨家霖
蔡冰洁
刘陈
吴文洁
杨维
李韶菁
LI Shuting;YANG Jiain;CAI Bingjie;LIU Chen;WU Wenjie;YANG Wei;LI Shaojing(Institute of Chinese Materia Medica,China Academy of Chinese Medical Sciences,Beijing 100700,China;Anhui University of Chinese Medicine,Hefei 230012,China)
出处
《中国中医药图书情报杂志》
2023年第6期18-23,共6页
Chinese Journal of Library and Information Science for Traditional Chinese Medicine
基金
国家重点研发计划(2017YFC1701900)
中国中医科学院科技创新工程项目(CI2021A02001、CI2021A04902)。
