摘要
目的:探讨青年初治肺结核患者在不同治疗时期的服药依从性及其影响因素,为制订精准服药管理策略,进而提高治疗成功率提供理论依据。方法:通过分层随机抽样的方法,选取2021年9月至2022年2月在新疆喀什地区就诊并登记在册的青年初治肺结核患者283例进行横断面调查,将患者按照接受标准化疗方案治疗的服药时间分为A(服药1~2个月)、B(服药3~4个月)、C(服药5~6个月)3组,分别为77、89、117例。采用一般资料调查问卷、8条目Morisky服药依从性量表和结核病患者遵医行为评定量表收集患者的临床资料。结果:3组青年初治肺结核患者服药依从良好者分别占93.5%(72/77)、89.9%(80/89)、82.1%(96/117),3组比较差异有统计学意义(χ^(2)=6.23,P<0.05)。Logistic回归分析显示,社会支持为服药第1~2个月的影响因素(OR=0.536,P<0.05);治疗信心和心理状况为服药第3~4个月的影响因素(OR=0.668、2.212,均P<0.05);合并症、社会支持、心理状况、应对方式为服药第5~6个月的影响因素(OR值为0.428~9.518,均P<0.05)。结论:青年初治肺结核患者在治疗的不同时期,影响其服药依从性的相关因素不尽相同,应根据各阶段的影响因素,制订精准的服药管理策略。
Objective To investigate the medication adherence and its influencing factors in young newly diagnosed pulmonary tuberculosis patients during different treatment periods,in order to provide a theoretical basis for formulating precise medication management strategies and thus improving the treatment success rate.MethodsA cross-sectional survey was conducted using a stratified random sampling method to select 283 young newly diagnosed pulmonary tuberculosis patients who visited and registered in the Kashgar region of Xinjiang from September 2021 to February 2022.The patients were divided into three groups according to the treatment time of receiving standard chemotherapy regimen:A(1-2 months of medication),B(3-4 months of medication),and C(5-6 months of medication),with 77,89,and 117 cases,respectively.The clinical data of tuberculosis patients were collected by using the general information questionnaire,Eight-Item Morisky Medication Adherence Scale and Tuberculosis Medication Adherence Scale for tuberculosis patients.ResultsThose who take medication well of three groups of young newly treated pulmonary tuberculosis patients were 93.5%(72/77),89.9%(80/89),and 82.1%(96/117),respectively.The difference among the three groups was statistically significant(χ^(2)=6.23,P<0.05).Logistic regression analysis showed that social support was an influential factor for the 1st to 2nd month of medication(OR=0.536,P<0.05);treatment confidence and psychological status were influential factors for the 3rd to 4th month of medication(OR=0.668,2.212,both P<0.05);comorbidity,social support,psychological status,and coping style were influential factors for the 5th to 6th month of medication(OR values were 0.428-9.518,all P<0.05).ConclusionsThe relevant factors that affect medication adherence vary among young newly diagnosed pulmonary tuberculosis patients at different stages of treatment.Accurate medication management strategies should be developed based on the influencing factors at each stage.
作者
蒋宇
杨静
吴茜
古丽苏木汗·阿布来提
施莉
夏迪亚·阿布来提
王梅新
Jiang Yu;Yang Jing;Wu Qian;Gulisumuhan Abulaiti;Shi Li;Xiadiya Abulaiti;Wang Meixin(School of Nursing,Xinjiang Medical University,Urumqi 830011,China;Department of Nursing,Xinjiang Kashgar Tuberculosis Prevention and Control Institute Hospital,Kashgar 844000,China;Department of Outpatient,Xinjiang Kashgar Tuberculosis Prevention and Control Institute Hospital,Kashgar 844000,China;Quality Supervision and Management Office,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830054,China)
出处
《中国实用护理杂志》
2023年第18期1388-1395,共8页
Chinese Journal of Practical Nursing
基金
中华护理学会2021年度立项科研课题项目(ZHKY202102)
新疆医科大学研究生创新创业项目(CXCY2022038)。
关键词
结核
肺
青年
服药依从性
影响因素
Tuberculosis,pulmonary
Youth
Medication adherence
Influencing factors
