摘要
目的探讨乌鲁木齐市中老年人体力活动量与肌肉减少症的剂量-反应关系,为指导中老年人合理安排运动提供参考。方法采用现况调查法,选取2018年12月至2019年12月乌鲁木齐慈惠健康管理中心的1886名中老年人(年龄≥50岁)作为研究对象,对其进行问卷调查,收集一般资料和体格检查数据,日常活动使用国际体力活动问卷长卷进行调查及评估,使用肌肉减少症亚洲工作组(AWGS)2019的诊断标准,对受调查者进行肌肉减少症的诊断。使用Logistic回归模型分析体力活动与肌肉减少症之间的关系,使用限制性立方样条分析体力活动与肌肉减少症的剂量-反应关系。结果被调查的1886名中老年人中,208名患有肌肉减少症,其患病率为11%。多因素分析结果显示,调整了人口学特征等混杂因素后,与低强度体力活动相比,中、高强度体力活动患肌肉减少症的风险降低(OR=0.390,95%CI 0.261~0.581;OR=0.055,95%CI 0.025~0.122)。体力活动与肌肉减少症间的剂量-反应关系显示,总体力活动量与肌肉减少症呈近似的"L"型剂量-反应关系(P<0.01)。结论体力活动量与肌肉减少症的关联强度呈近似的"L"型的曲线,当体力活动量在2500~3500 MET-min/周时,增加体力活动量可降低肌肉减少症的患病风险。
Objective To investigate the dose-response relationship between physical activity and sarcopenia in middle-aged and elderly people in Urumqi,and then provide the reference to guide the middle-aged and elderly people to arrange exercise reasonably.Methods A total of 1886 middle-aged and elderly people(aged≥50 years old)from December 2018 to December 2019 in Cihui Health Management Center in Urumqi were selected as the research objects to conduct a questionnaire survey,collected general information and physical examination data,and used the International Physical activity questionnaire to investigate and evaluate their daily activities.Diagnostic criteria of the Asian Working Group on Sarcopenia(AWGS)2019 were used.Logistic regression model was used to analyze the relationship between physical activity and sarcopenia,and restricted cubic spline was used to analyze the dose-response relationship between physical activity and sarcopenia.Results Among the investigated subjects,208 people suffered from sarcopenia,and the prevalence rate was 11%.Multivariate analysis showed that after adjusting for confounding factors such as demographic characteristics,moderate and high intensity physical activity was associated with a lower risk of sarcopenia compared with low intensity physical activity(OR=0.389,95%CI 0.261-0.580;OR=0.055,95%CI 0.025-0.122).The dose-response relationship between physical activity and sarcopenia showed an approximate 1-shaped dose-response relationship between total physical activity and sarcopenia(P<0.01).Conclusions The strength of the association between physical activity and sarcopenia was approximately an"L"shaped curve,and increased physical activity was associated with a lower risk of sarcopenia when physical activity was between 2500 and 3500 MEt-min/week.
作者
樊海源
谢会群
韩晓丽
姚雪梅
Fan Haiyuan;Xie Huiqun;Han Xiaoli;Yao Xuemei(Public Health School,Xinjiang Medical University,Urumqi 830011,China;Department of Clinical Natrition,Urumqi Friendship Hospital,Urumqi 830049,China)
出处
《中国实用护理杂志》
2023年第11期831-837,共7页
Chinese Journal of Practical Nursing
基金
新疆维吾尔自治区自然科学基金项目(2016D01C187)。
关键词
肌减少症
中老年人
体力活动
剂量-反应关系
Sarcopenia
Middle aged and elderly
Physical activity
Dose-response relationship
