摘要
目的通过系统评价与Meta分析探究社区老年人肌少症发病率及危险因素。方法检索从建库到2021年1月PubMed、Web of Science、the Cochrane Library、知网、万方等中英文数据库,纳入肌少症发病率及其影响因素的队列研究。采用软件STATA15.0和Review Manager 5.4对社区老年人肌少症发生率及影响因素进行分析。结果共纳入13篇文献,13750例研究对象。结果显示,肌少症发生率为11%,随访1~2年、3~4年社区老年人肌少症发病率分别为6%和12%,亚洲地区发病率分别为9%,亚洲之外地区为13%,女性发病率为16%,男性为11%。从危险因素来看:高龄(OR=1.11,95%CI:1.09~1.12,P<0.00001)、中风史(OR=2.92,95%CI:1.60~5.31,P=0.0005)、低BMI(OR=1.51,95%CI:1.42~1.60,P<0.00001)、缺乏运动(OR=1.44,95%CI:1.18~1.76,P=0.0003)是社区肌少症的重要危险因素。结论社区老年人肌少症发生率较高,高龄、中风史、低BMI、缺乏运动是肌少症的重要危险因素。
Objective To evaluate the incidence and risk factors of sarcopenia in the elderly in community using meta-analysis method.Methods We collected data from database including PubMed,Web of Science,the Cochrane Library,China Hownet,and Wanfang from their establishment to January 2021.Cohort studies about incidence of sarcopenia and its influencing factors were included.The statistic data are calculated using Review Manager 5.4 and STATA 15.0 software.Results Thirteen articles and 13,750 subjects were included.The result showed that the incidence of sarcopenia was 11%.The incidences of sarcopenia were 6%and 12%at 1-2-year and 3-4-year follow-up,respectively.The incidences in Asian region and in the non-Asian region were 9%and 13%,respectively.They were 16%in women and 11%in men,respectively.In terms of risk factors,advanced age(OR=1.11,95%CI:1.09-1.12,P<0.00001),history of stroke(OR=2.92,95%CI:1.60-5.31,P=0.0005),low BMI(OR=1.51,95%CI:1.42-1.60,P<0.00001),and lack of exercise(OR=1.44,95%CI:1.18-1.76,P=0.0003)were important risk factors for community sarcopenia.Conclusion The incidence of sarcopenia in the elderly in community is high.Senior age,low BMI,history of stroke,and lack of exercise are the important risk factors for sarcopenia.
作者
罗旺辉
魏琳
梁好
张小培
刘竹韵
廖若彤
陈蕊
罗尧岳
LUO Wanghui;WEI Lin;LIANG Hao;ZHANG Xiaopei;LIU Zhuyun;LIAO Ruotong;CHEN Rui;LUO Xiaoyue(College of Nursing, Hunan University of Traditional Chinese Medicine, Changsha 410208, China;The Second Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510120, China;The Second Clinical Medical College, Guangzhou University of Traditional Chinese Medicine, Guangzhou 510006, China)
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2022年第3期426-433,共8页
Chinese Journal of Osteoporosis
基金
广州中医药大学人文社会科学项目(20215KYB04)。
